Amoxicillin is an antibiotic drug to treat diseases caused by bacterial infections, such as otitis media, gonorrhea, or pyelonephritis. This drug is also often used with proton pump inhibitors (PPIs) to treat stomach ulcers caused by H. pylori bacteria .

Amoxicillin works by inhibiting the proteins that make up the bacterial cell wall, so that the cell wall is not formed, bacterial growth stops, and eventually dies. Amoxicillin is not used to treat viral infections, including the flu or Covid-19.

Amoxicillin trademarks: Amobiotic, Amoxicillin Trihydrate, Amoxsan, Betamox, Clamixin, Dexyclav Forte, Erlamoxy, Etamox, Holimox, Hufanoxil, Omemox, Pehamoxil, Pritamox, Supramox, Topcillin

What is Amoxicillin

class Prescription drug
Category Penicillin antibiotics
Benefit Treat bacterial infections, including gonorrhea, otitis media , or pyelonephritis
Used by Adults and children
Amoxicillin for pregnant and lactating women


Category B: Animal studies have shown no risk to the fetus, but there have been no controlled studies in pregnant women.

Amoxicillin can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Tablets, syrup, capsules and injections

Warnings Before Using Amoxicillin

There are several things that you should pay attention to before using amoxicillin, including:

  • Tell your doctor about any allergies you have. Amoxicillin should not be given to patients who are allergic to this drug or to other penicillin class antibiotics, such as ampicillin .
  • Tell your doctor if you have or currently have kidney disease , diarrhea, blood disorders , or mononucleosis .
  • Tell your doctor if you plan to vaccinate with a live vaccine, such as the BCG vaccine, while taking amoxicillin, as this medicine may decrease the effectiveness of the vaccine.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Report to your doctor any allergic drug reactions , serious side effects, or overdose after using amoxicillin.

Amoxicillin Dosage and Rules

The dose of amoxicillin given by the doctor depends on the condition you want to treat, age, dosage form of the drug, and the type and severity of the infection. Injectable amoxicillin will be injected directly by a doctor or medical officer under the supervision of a doctor. Here is the explanation:

Purpose: Overcome bacterial infections

Form: Tablet, syrup or capsule

  • Adult: 250–500 mg, every 8 hours or 500–1,000 mg, every 12 hours. For severe infections the dose is 750-1000 mg, every 8 hours.
  • Children >3 months of age <40 kg: 20–90 mg/kg per day.

Shape: Syringe

  • Adult: 500 mg, every 8 hours by injection into a muscle (intramuscularly/IM) or into a vein (intravenous/IV).
  • Children >3 months old <40 kg: 20–200 mg/kg, 2–4 times daily.

Purpose: Overcome pharyngitis or tonsillitis due to Streptococcus infection

Form: Tablet, syrup or capsule

  • Adult: 500 mg every 8 hours or 750–1000 mg every 12 hours. For severe infections the dose is 750–1000 mg, every 8 hours, for 10 days.
  • Children weighing <40 kg: 40–90 mg/kg per day divided into several doses.

Purpose: Overcoming gonorrhea

Form: Tablet, syrup or capsule

  • Adults: The dose is 3,000 mg as a single dose. The drug will be combined with probenecid.

Purpose: Treat stomach ulcers caused by H. pylori bacteria

Form: Tablet, syrup or capsule

  • Adult: 750–1,000 mg, 2 times daily for 7–14 days. The drug will be combined with proton pump inhibitors (PPIs), such as omeprazole.

How to Use Amoxicillin Properly

Follow the doctor 's advice and recommendations while you are undergoing treatment with amoxicillin. Do not increase your dose, reduce your dose, or stop your medication without first consulting your doctor.

Injectable amoxicillin will be given by a doctor, or medical staff under the supervision of a doctor. Amoxicillin syrup, tablets or capsules can be taken before or after meals.

If you are taking Amoxicillin in syrup form, shake the medicine thoroughly first, then take the medicine according to the dosage using a measuring spoon.

If you forget to take amoxicillin, take this medicine immediately if it is not close to the schedule for taking the next drug. If it is close, ignore the missed dose and do not double the dose.

Store amoxicillin in a place away from direct sunlight. Keep this medicine out of reach of children.

Amoxicillin Interactions with Other Drugs

The following are a number of interaction effects that can occur when amoxicillin is used with other drugs:

  • Decreased effectiveness of birth control pills
  • Increased levels of amoxicillin in the blood when used with probenecid
  • Decreased effectiveness of live vaccines, such as typhoid vaccine or  BCG vaccine
  • Increased levels of methotrexate in the blood, thereby increasing the risk of side effects
  • Increased risk of allergic reactions when used with allopurinol
  • Decreased effectiveness of amoxicillin when used with chloramphenicol , macrolides, sulfonamides, or tetracycline HCl
  • Increased risk of bleeding if used with blood-thinning medications , such as warfarin

Side Effects and Dangers of Amoxicillin

Tell your doctor or medical officer if the following side effects do not subside or get worse:

  • Changes in taste on the tongue
  • Nausea or vomiting
  • Headache
  • Diarrhea

In addition, report to your doctor immediately if you experience an allergic reaction to the drug or experience more serious side effects, such as:

  • Fast or irregular heartbeat
  • Easy bruising
  • Severe diarrhea that doesn't go away, bloody stools, or severe stomach cramps
  • Jaundice or dark urine
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