Anastrozole is a drug to treat breast cancer in menopausal women. Anastrozole can be given to patients whose condition does not improve after undergoing treatment with tamoxifen.
Anastrozole works by lowering estrogen levels in the body by inhibiting the aromatase enzyme. That way, it is hoped that the size of the tumor will shrink and the growth of cancer cells can be inhibited.
Please note, anastrazole should not be used by men, children or women who have not reached menopause.
Anastrozole trademarks : Anamidex, Anzonat, Aramidex, ATZ, Bracer, Brecazole
What is Anastrozole
|Benefit||Treating breast cancer in postmenopausal women|
|Anastrozole for pregnant and lactating women||
Category X: Studies in experimental animals and humans have demonstrated fetal abnormalities or a risk to the fetus. Drugs in this category should not be used by women who are or may become pregnant.
Anastrozole is not known to be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.
Precautions Before Taking Anastrozole
There are several things you should pay attention to before using anastrozole, namely:
- Tell your doctor about any history of allergies you have. Anastrozole should not be given to patients who are allergic to this drug.
- Tell your doctor if you haven't gone through menopause . Anastrozole should not be given to patients with these conditions.
- Tell your doctor if you have or have ever had liver disease, coronary heart disease , heart disease, high cholesterol , hypertension, osteoporosis , blood clotting disorders, or low bone density.
- Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy. Use effective contraception while on treatment with this drug.
- Tell your doctor if you are taking certain medications, supplements or herbal products.
- See your doctor right away if you experience an allergic drug reaction , overdose, or serious side effect after using anastrozole.
Dosage and Rules for Use Anastrozole
The dose of anastrozole as an adjunct therapy for treating breast cancer in postmenopausal women is 1 mg, once a day. The duration of treatment can be done up to 5 years
The doctor will adjust the dose given according to the patient's age, condition, and body's response to treatment.
How to Take Anastrozole Correctly
Always follow the doctor 's instructions and read the information on the drug packaging before taking anastrozole
Anastrozole can be taken before or after meals. Take anastrozole at around the same times each day. Swallow the anastrozole tablets whole with the help of a glass of water. Do not crush, split or chew the medication as this can affect its effectiveness.
Take anastrozole regularly. Do not start or stop taking medication or increase or decrease the dose of medication without consulting your doctor first.
If you forget to take anastrozole tablets, take them as soon as you remember if the distance to the next consumption schedule is not too close. If it is close, ignore it and do not double the dose.
Anastrozole can cause reduced bone density. Therefore, you will be asked to have a bone density test before and during treatment with this drug.
Store anastrozole in a dry place, away from direct sunlight, and at room temperature. Keep this medicine out of reach of children.
Anastrozole Interactions with Other Drugs
Some of the interaction effects that can occur when anastrozole is used together with other drugs include:
- Increased risk of forming clots and blood clots that can block blood vessels when used together with thalidomide
- Decreased effect of anastrozole when used concurrently with estrogen or estrogen-containing drugs
- Decreased blood levels of anastrozole when used concurrently with tamoxifen
Anastrozole Side Effects and Dangers
There are several side effects that can appear after taking anastrozole, including:
- Hot flashes
- Nausea or vomiting
- Stomach ache
- Constipation or diarrhea
- No appetite
- Weight gain
- Weak or tired
- Sore throat
Check with your doctor if these side effects don't improve or get worse. Immediately see a doctor if you experience an allergic drug reaction or the following serious side effects:
- Bone pain
- Bones break or crack easily
- Joint pain or stiffness in the joints
- Stiff or sore muscles
- Mood swings
- Numbness or tingling
- Short breath
- Excessive vaginal discharge, painful vaginal discharge, or vaginal itching
- Swelling in the hands, feet or ankles
- Chest pain or weakness on one side of the body
- Vision changes, such as blurry vision
- Severe nausea or vomiting, severe stomach pain, jaundice