Antihistamine

Antihistamine

Antihistamines are a group of drugs used to relieve complaints or symptoms due to allergic reactions, for example in allergic rhinitis or urticaria.  In addition, several types of antihistamines can also be used to relieve nausea or vomiting, especially from motion sickness.

Antihistamines work by blocking the action and amount of histamine. Histamine is a chemical substance that will cause an allergic reaction, when someone who is allergic is exposed to an allergy-triggering substance (allergen). That way, the symptoms due to an allergic reaction can subside.

Although they can relieve symptoms due to allergic reactions including  skin allergies , antihistamines cannot cure allergies. The best way to prevent an allergic reaction from occurring is to avoid exposure to the triggering substance or ingredients.

Several types of antihistamines can also block nerve signals in the brain that control the response to nausea or vomiting, so they can sometimes be used to relieve nausea and vomiting, especially due to motion sickness .

Antihistamines are divided into 3 types, namely first, second, and third generation antihistamines. First-generation antihistamines have a way of working that passes through the lining of the brain, so they can cause drowsiness. While the second and third generations do not pass through the lining of the brain, so they are less likely to cause drowsiness.

Warning Before Using Antihistamines

There are several things that you should pay attention to before using antihistamines, namely:

  • Do not use antihistamines if you are allergic to these drugs. Always tell your doctor about any allergies you have.
  • Tell your doctor if you have or have had heart disease , an enlarged prostate, thyroid disease , high blood pressure, kidney disease, liver disease, difficulty urinating, epilepsy , or glaucoma .
  • Do not drive a vehicle or do activities that require alertness after taking antihistamines, especially the first generation, because they can cause drowsiness or dizziness.
  • Do not drink alcohol while you are taking antihistamines, as this increases the risk of side effects.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • See your doctor right away if you have an allergic reaction , serious side effects, or overdose after taking antihistamines.

Side Effects and Dangers of Antihistamines

There are several side effects that can occur after using antihistamines, including:

  • Headache
  • Dizzy
  • Blurred vision
  • Drowsiness
  • Agitation
  • Stomach ache
  • Difficulty urinating
  • Dry mouth

Check with your doctor if the side effects above don't get better or get worse. In addition, if taken in excessive amounts, first-generation antihistamines can cause more serious side effects, such as excessive but unnatural pleasure (euphoria) or loss of consciousness, to delirium .

Immediately consult a doctor if you experience these side effects or experience an allergic drug reaction after using antihistamines.

Types and Trademarks of Antihistamines

The following are types of antihistamine drugs equipped with trademarks, as well as dosages that are adjusted to the condition and age of the patient:

First Generation Antihistamines

1. Chlorpheniramine

Trademarks: Brontusin, Ceteem, Chlorpheniramine, Chlorpheniramine Maleate, Cough En Plus, Etaflusin, Molexflu, Nalgestan, Omecough, Samcodin, Zacoldine

To find out the dosage and further information about this drug, please open the chlorpheniramine drug page .

2. Cyproheptadine

Merek dagang: Bimatonin, Cydifar, Ennamax, Erphacyp, Graperide, Heptasan, Lexahist, Lycipron, Profut, Pronam, Pronicy

To find out the dosage and further information about this drug, please open the cyproheptadine drug page .

3. Ketotifen

Trademarks: Astifen, Ertifen, Intifen, Profilas, Scanditen, Tosma, Zaditen

To find out the dosage and further information about this drug, please open the ketotifen drug page .

4. Promethazine

Merek dagang: Berlifed, Bufagan Expectorant, Erpha Allergil, Gigadryl, Guamin, Hufallerzine Expectorant, Metagan Expectorant, Mezinex, Nufapreg, Phenerica, Prome, Promedex, Promethazine, Prozine Expectorant, Rhinathiol Romethazine,  Winasal, Zenirex

To find out the dosage and more information about this drug, please visit the promethazine drug page .

5. Triprolidine

Merek dagang: Actifed, Alerfed Plus Expectorant, Bronchitin, Ersylan Expectorant, Lapifed, Librofed, Quantidex

To find out the dosage and further information about this drug, please open the triprolidine drug page .

6. Brompheniramine

Trademarks: Alco Plus, Alco Plus DMP, Bromphenyl

To find out the dosage and further information about this drug, please open the brompheniramine drug page .

7. Hydroxyzine

Trademark: Bestalin

To find out the dosage and further information about this drug, please open the hydroxyzine drug page .

8. Doxylamine

Trademarks: Dexmolex, Oradex, Siladex Cough & Cold, Vicks Formula 44

To find out the dosage and more information about this drug, please visit the doxylamine drug page .

Second Generation Antihistamines

1. Cetirizine

Merek dagang: Alergia, Allerzen, Cerini, Cetinal, Cetirizine HCl, Cetirizine Hydrochloride, Etarizine, Falergi, Ozen, Rinocet, Yarizine, Zentris

To find out the dosage and more information about this drug, please visit the cetirizine drug page .

2. Loratadine

Trademarks: Deslo, Inalergi, Inclarin, Lorhis, Loratadine, Lorahistin, Omellegar

To find out the dosage and further information about this drug, please open the loratadine drug page .

3. Levocetirizine

Trademarks: Avocel, Levocetirizine Dihydrochloride, Histrine Levo, L-Allergy, Xyzal

To find out the dosage and further information about this drug, please open the levocetirizine drug page .

4. Astemizole

Trademarks: -

To find out the dosage and more information about this drug, please visit the astemizole drug page .

Third Generation Antihistamines

1. Fexofenadine

Merek dagang: Fexoven OD, Telfast,Telfast BD, Telfast HD, Telfast OD, Telfast Plus

To find out the dosage and further information about this drug, please open the fexofenadine drug page .

2. Desloratadine

Trademarks: Aerius, Desdin, Desfumed, Desloratadine, Deslotine, Destavell, Eslor

To find out the dosage and more information about this drug, please visit the desloratadine drug page .

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