Bismuth Subsalicylate

Bismuth Subsalicylate

Bismuth subsalicylate is a medication used to treat diarrhea in adults and adolescents. This medication can also be used to relieve stomach pain, heartburn, or nausea.

Bismuth subsalicylate works by slowing the growth of bacteria that cause diarrhea. In addition, this drug also has an anti-inflammatory effect and the ability to trigger the reabsorption of fluids and electrolytes, thereby reducing fluid loss due to diarrhea.

Bismuth subsalicylate can also be used to treat Helicobacter pylori infection , and its use will be combined with other drugs .

Bismuth subsalicylate trademarks: Neo Adiar, New Sybarin, Scantoma

What is Bismuth Subsalicylate

group Limited over-the-counter drugs
Category Diarrhea medication
Benefit Overcome diarrhea, heartburn, and stomach pain
Consumed by Adults and children 12 years and over
Bismuth subsalicylate for pregnant and lactating women Category C:  Studies in experimental animals show an adverse effect on the fetus, but there are no controlled studies in pregnant women. The drug should only be used if the expected benefit outweighs the risk to the fetus.

Category D (in the third trimester): There is positive evidence of risk to the human fetus, but the benefits may outweigh the risks, for example in dealing with a life-threatening situation.

Bismuth subsalicylate can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Tablets and caplets

Warning Before Consuming Bismuth Subsalicylate

Before taking this drug, you need to pay attention to the following things:

  • Do not take bismuth subsalicylate if you are allergic to this drug. Tell your doctor about any history of allergies you have.
  • Tell your doctor if you have or have had  dysentery , gout, peptic ulcers, von Willebrand's disease, kidney disease, hemophilia , or any other blood disorder.
  • Talk to your doctor about using bismuth subsalicylate in children, especially those with chickenpox or influenza, because of the possibility of Reye 's syndrome .
  • Tell your doctor that you are taking bismuth subsalicylate before having a radiological examination, as this medicine can affect the results of radiological examinations of the digestive system.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
  • Immediately see a doctor if you have an allergic drug reaction, serious side effects, or an overdose after taking bismuth subsalicylate.

Bismuth Subsalicylate Dosage and Use Rules

The following is a general dose of bismuth subsalicylate which is grouped based on the patient's condition:

Condition:  Diarrhea , heartburn, nausea, stomach pain

  • Adults and children 12 years and older: 524 mg every 30–60 minutes. Do not exceed 8 drinks in 24 hours.

Condition:  Helicobacter pylori infection

  • Adult: 524 mg, combined with metronidazole and tetracycline, 4 times daily.

How to Take Bismuth Subsalicylate Correctly

Follow the doctor 's advice and read the information listed on the drug packaging label before taking bismuth subsalicylate. Do not reduce or increase the dose without consulting your doctor first.

Bismuth subsalicylate can be taken before or after meals. Swallow the medicine whole with the help of a glass of water. Do not crush or chew tablets or caplets.

If the drug is used to treat diarrhea , it is advisable to drink lots of water. Avoid consuming fruits, vegetables, fried foods, spicy foods, sweets, caffeine, or alcoholic beverages, as they can make diarrhea worse.

Store bismuth subsalicylate at room temperature and avoid direct sunlight. Keep this drug out of reach of children.

Interactions of Bismuth Subsalicylate with Other Drugs

The following are drug-drug interactions that may occur if bismuth subsalicylate is used with other drugs:

  • Decreased therapeutic effect of sulfinpyrazone,  doxycycline , tetracycline, or probenecid
  • Increased levels of methotrexate in the blood
  • Increased risk of bleeding if used with blood-thinning medications, such as  clopidogrel or warfarin
  • Increased risk of side effects when used with pain relievers, such as ibuprofen or naproxen
  • Increased risk of overdose if used with drugs containing salicylates, such as  aspirin 

Bismuth Subsalicylate Side Effects and Dangers

The most common side effect after using bismuth subsalicylate is a blackish color of the stool or tongue. Check with your doctor if these side effects do not subside.

In addition, you should see a doctor immediately if you experience an allergic drug reaction or any of the following serious side effects:

  • Black vomit
  • Bloody or black stools
  • Severe stomach pain
  • Sudden ringing in the ears or deafness
Back to blog