Budesonide is a corticosteroid drug used to treat various inflammatory conditions, such as asthma, allergic rhinitis, croup , or Crohn's disease . This drug is available in various dosage forms, namely inhalers, liquid nebulizers, nasal sprays, and capsules.

Budesonide inhalers and nebulizer liquids work by reducing inflammation in the respiratory tract, so they are often used in asthma and croup .

While budesonide nasal spray works by inhibiting the release of natural compounds that trigger allergy symptoms. This medication can be used to relieve symptoms of allergic rhinitis due to exposure to allergens, such as pollen ( hay fever ), dust, mold, or pet dander.

In addition, budesonide in capsule form is used in the treatment of Crohn's disease, ulcerative colitis, or autoimmune hepatitis.

Budesonide trademarks: Budesonide, Budesma, Budenofalk, Cortiment, Sonide, Symbicort

What is Budesonide

group Prescription drug
Category Corticosteroids
Benefit Manage and relieve symptoms of asthma, croup , allergic rhinitis or Crohn's disease
Used by Adults and children
Budesonide for pregnant and lactating women Category B (inhaler forms, nebulizer liquid, and nasal spray): Animal studies have not demonstrated a risk to the fetus, but there are no controlled studies in pregnant women.

Category C (capsule form): Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Budesonide Inhaler, nebulizer liquid, and nasal spray may be absorbed into breast milk. While budesonide capsules are not yet known to be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Inhalers, nebulizer liquids, nasal sprays, capsules

Precautions Before Using Budesonide

Budesonide should only be used as prescribed by a doctor. Here are some things you need to pay attention to before using budesonide:

  • Tell your doctor about any history of allergies you have. Budesonide should not be used in patients who are allergic to this drug.
  • Tell your doctor if you have or have had high blood pressure, diverticulitis , osteoporosis, thyroid disease , epilepsy, cataracts , or myasthenia gravis .
  • Tell your doctor if you have or are currently suffering from tuberculosis , an infectious disease, heart disease, a heart attack , a stomach ulcer, or a mental disorder, such as depression .
  • If you want to use budesonide nasal spray, tell your doctor if you have recently had nose surgery or have had any injuries and sores to your nose.
  • Do not consume alcoholic beverages while you are taking budesonide, because this will increase the risk of side effects.
  • As much as possible, avoid close contact with people with infectious diseases that are easily transmitted, such as chickenpox or measles, because these drugs can make it easier for you to get an infection.
  • Tell your doctor if you plan to get vaccinated while on treatment with budesonide, because this medication may reduce the effectiveness of the vaccine.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after using budesonide.

Dosage and Rules for Use of Budesonide

The dose of budesonide given by the doctor depends on the patient's health condition and the dosage form of the drug. Here is the explanation:

Condition: Asthma

  • Forms: Inhaler
    Adults: 0.2–0.8 mg per day, divided into 1–2 doses. The maximum dose is 0.8 mg per day.
  • Forms: Liquid nebulizer
    Adults: 1–2 mg, 2 times daily. Maintenance dose 0.5–1 mg, 2 times daily.

Condition: Croup

  • Forms: Nebulizer liquid
    Children: 2 mg as a single dose. If needed, the drug can be used every 12 or 36 hours.

Conditions: Allergic rhinitis and nasal polyps

  • Forms: Nasal spray
    Adults and children ≥6 years: 1–2 sprays into each nostril, 2 times daily.

Condition: Crohn's Disease

  • Form:
    Adult Capsules : 9 mg, once daily, before breakfast. The drug can be taken for 8 weeks.

How to Use Budesonide Correctly

Follow the doctor 's advice and read the information on the medicine package before using budesonide. Do not increase or decrease the dose without consulting your doctor first.

If you take budesonide capsules, swallow them whole with the help of water. Do not chew, split, or crush the medicine as this may increase the risk of side effects.

To use the budesonide inhaler, unlock the safety lock on the inhaler package. Exhale first before inhaling from the inhaler. Place the muzzle of the inhaler in your mouth. Close your lips tightly, then take a deep breath. Do not bite the muzzle of the inhaler.

After inhaling from the inhaler, hold your breath for 10 seconds and repeat the previous steps if advised by your doctor. Don't forget to close the inhaler again with the safety lock, then rinse your mouth with clean water.

If you are using a budesonide nebulizer, follow the instructions given by your doctor and make sure you understand how to use the nebulizer and how to clean it properly to prevent infection.

To use budesonide nasal spray, clean your nose first. Shake the nasal spray before use. Unscrew the spray bottle, then close one nostril with your finger.

Tilt your head slightly down to keep the spray bottle upright. Gently insert the tip of the bottle into the open nostril, then press the pump to inject the medication.

After that, remove the nozzle from the nostril and tilt your head up for a few seconds while pressing on the bridge of your nose so that the medicine doesn't spread into your mouth.

Take budesonide at the same time each day. If you forget to use it, start using budesonide as soon as the next scheduled break is not too close. If it's close, ignore it and don't double the dose.

Store budesonide at room temperature and in a closed container, away from direct sunlight. Keep this drug out of reach of children.

Interactions of Budesonide with Other Drugs

There are several side effects of drug interactions that may occur if budesonide is used with certain drugs, including:

  • Decreased absorption of budesonide when used with cholestyramine or antacids
  • Decrease in vaccine effectiveness
  • Increased risk of developing hypokalemia when used with diuretic drugs
  • Increased risk of side effects from budesonide when used with ketoconazole , itraconazole, clarithromycin , or cobicistat
  • Decreased effectiveness of budesonide when used with carbamazepine or rifampicin

Budesonide Side Effects and Dangers

Some of the side effects that can occur after using budesonide capsules are:

  • Dizzy
  • Headache
  • Feel tired
  • Thin skin and easy bruising
  • Stomach pain, nausea, vomiting, bloating , or constipation
  • Pain when urinating
  • Irregular menstruation
  • Nasal congestion , sneezing, or sore throat
  • Loss of sexual desire in men

Side effects that can occur after using the budesonide inhaler are:

  • Hoarseness
  • Cough or sneeze
  • Dry feeling in the throat
  • Headache
  • Joint pain or muscle pain
  • Nausea or vomiting
  • Decreased appetite

Side effects that can occur after using budesonide nasal spray are:

  • Nose feels dry or burning
  • Weak
  • Nausea or vomiting
  • Muscle and joint pain
  • Nosebleed

Check with your doctor if the complaints mentioned above do not go away or get worse. Stop using budesonide immediately and check with your doctor if you experience an allergic drug reaction after using budenoside.

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