Bupropion

Bupropion

Bupropion is a medicine to treat depression . This drug can also be used to help overcome smoking addiction. Bupropion should only be used under a doctor's prescription.

Bupropion works by balancing the levels of certain chemicals in the brain. Besides being able to relieve symptoms of depression, this method is also thought to reduce withdrawal symptoms from nicotine which are commonly felt by heavy smokers after quitting smoking. That way, the desire to smoke again can be reduced.

While undergoing treatment with bupropion, patients are recommended to undergo regular check-ups to the doctor so that their condition can continue to be monitored. In overcoming smoking addiction, the use of bupropion must also be accompanied by counseling and education.

Trademarks: -

What is Bupropion

group Antidepressants
Category Prescription drug
Benefit Overcome depression and help overcome smoking addiction ( nicotine addiction )
Consumed by Adults and seniors
Bupropion for pregnant and lactating women  Category C: Animal studies have shown adverse effects on the fetus, but there have been no controlled studies in pregnant women. Drugs should only be used if the expected benefit exceeds the risk to the fetus. If you are pregnant, do not use this drug without consulting a doctor first.

Bupropion can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Tablet

Warnings Before Taking Bupropion

There are several things that you should pay attention to before taking bupropion, including:

  • Do not use bupropion if you have a history of allergies to this drug. Always tell your doctor about any allergies you have.
  • Do not use bupropion within 2 weeks before or after taking an MAOI drug .
  • Avoid consuming alcoholic beverages while using bupropion, as this can increase the risk of side effects.
  • Do not use bupropion if you have epilepsy , or eating disorders, such as anorexia and bulimia .
  • Tell your doctor if you have or currently have a mental disorder , such as bipolar disorder , drug addiction, psychosis , or schizophrenia .
  • Tell your doctor if you have or have had seizures, tumors in the brain or spine, head injury, hyponatremia , diabetes, glaucoma , kidney disease, or liver disease, especially cirrhosis .
  • Tell your doctor if you have a cardiovascular disease, such as hypertension , heart attack, or stroke .
  • Tell your doctor if you consume alcoholic beverages, sleeping pills, or anticonvulsant drugs every day, because the doctor must make adjustments first to avoid side effects or drug interactions. Also tell if you are taking other medicines, including herbal medicines and supplements.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Do not drive a vehicle or perform activities that require alertness while using bupropion, because this drug may cause dizziness or drowsiness.
  • Immediately see a doctor if you experience a drug allergic reaction , overdose, or serious side effects after using bupropion,

Dosage and Instructions for Use of Bupropion

The dose of bupropion will be adjusted according to the drug preparation, age, and patient tolerance to the drug. The following dosages of bupropion are based on their intended use:

Purpose: Treat depression

Tablet form

  • Adult: Initially 100 mg twice daily for 3 days. If needed, the dose may be increased to 100 mg 3 times daily. If the patient's condition does not improve after several weeks of treatment, the dose can be increased to 150 mg 3 times a day. The maximum dose is 150 mg 3 times a day.
  • Elderly: Dosage will be determined based on the patient's condition and response to treatment.

Modified release tablet form

  • Adult: 150 mg once daily. If needed, the dose may be increased to 150 mg twice daily after 3 days. The dose may be increased back to 200 mg twice daily after a few weeks if needed. Maximum dose is 450 mg as a single dose.
  • Elderly: The dose will be determined based on the patient's condition and the patient's response to treatment.

Goal: Stop smoking

Modified release tablet form

  • Adult: Initially 150 mg once daily for 6 days. Follow-up dose 150 mg twice daily for 7–9 weeks. Give a gap of at least 8 hours between the two doses. Stop treatment if after 7 weeks the patient still has the urge to smoke. The maximum dose is 300 mg per day.
  • Elderly: 150 mg once daily for 7–9 weeks.

How to Take Bupropion Correctly

Always follow the doctor 's instructions and read the information on the medicine package. Do not decrease or increase the dose of the drug without consulting your doctor, as this may increase the risk of side effects.

Bupropion can be taken before or after meals. However, to prevent nausea or stomach pain, it is best to take this drug after eating.

Swallow the bupropion tablet whole with the help of a glass of water. Do not chew, split, or crush modified release tablets , as this may affect the effectiveness of the drug.

Take this medicine regularly at the same time every day. If you forget to take bupropion, take it as soon as it is not near your next schedule. If it is close, ignore the missed dose and do not double the next dose.

Consult your doctor regularly while undergoing treatment with this drug. Follow the control schedule given by the doctor. Your doctor may adjust the dose of bupropion based on your condition.

Do not stop using bupropion without first discussing it with your doctor. Stopping bupropion suddenly can cause withdrawal symptoms, such as increased appetite, weight gain, difficulty sleeping and concentrating, anxiety, depression, or irritability.

In general, the benefits of the drug can be seen after 4 weeks of treatment. Immediately consult a doctor if your condition does not improve or even gets worse after taking bupropion.

Store bupropion at room temperature. Keep this medicine away from heat, humid air, direct sunlight, and out of reach of children.

Bupropion Interactions with Other Drugs

Drug interaction effects that can occur if bupropion is used together with other drugs are:

  • Increased risk of dangerous side effects when used with MAOI drugs
  • Increased risk of side effects when used with levodopa or amantadine
  • Increased risk of side effects from venlafaxine, fluoxetine, antipsychotics, beta blockers , or propafenone
  • Increased risk of seizures, if used with other antidepressants, antipsychotics , theophylline , or systemic corticosteroids
  • Decreased effectiveness of bupropion when used with ritonavir, lopinavir, or efavirenz

Side Effects and Dangers of Bupropion

Some of the side effects that may arise after taking bupropion include:

  • Dry mouth , sore throat, stuffy nose
  • Ringing ears
  • Blurred vision
  • Nausea, vomiting, abdominal pain, loss of appetite, constipation
  • Sleep disturbances, such as insomnia
  • Tremors, excessive sweating, anxiety, or nervousness
  • Rapid heartbeat
  • Dazed, irritable, or irritable
  • skin rash
  • Weight gain
  • Increased frequency of urination
  • Headache or dizziness
  • Muscle or joint pain

Check with your doctor if these side effects don't go away or get worse. See your doctor right away if you have an allergic reaction to a drug or a more serious side effect, such as:

  • Seizure
  • Changes in mood or unusual behavior
  • Narrowing of the field of view ( tunnel vision ), a halo appears when looking at a light source, and the eyes feel sore or swollen
  • Faster or irregular heartbeat
  • The manic phase, which can be characterized by the emergence of flashing ideas and thoughts; full of vigor and energy; very happy or very irritable; talk more than usual; or feel no need to sleep
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