Carbapenems

Carbapenems

Carbapenems are a group of antibiotics used to treat gram-positive or gram-negative bacterial infections, such as infections of the respiratory tract and lungs, skin, or urinary tract. This drug is a type of beta-lacta antibiotic .

Carbapenems kill bacteria by inhibiting the formation of the bacterial cell wall. Carbapenems can also sometimes be combined with other antibiotics to treat bacterial infections that are resistant to several types of antibiotics ( multi-drug resistance ).

Carbapenem is available in injectable form and can only be given by a doctor or medical officer under the supervision of a doctor. Drugs that are included in the carbapenem antibiotics are biapenem, doripenem, ertapenem, imipenem-cilastatin, and meropenem.

Precautions Before Using Carbapenem

There are several things that you should pay attention to before using carbapenems, including:

  • Tell your doctor about any history of allergies you have. Carbapenems should not be given to patients who are allergic to this drug or to other beta-lactams, such as penicillins .
  • Tell your doctor if you have had or are currently having kidney disease , stroke, meningitis, head injury , brain tumor, colitis , or seizures .
  • Tell your doctor if you are taking antiseizure medications, such as valproic acid or sodium valproate.
  • Consult your doctor if you plan to get vaccinated while taking carbapenems.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking any medications, supplements or herbal products.
  • Report to your doctor if you have an allergic drug reaction, serious side effects, or overdose after using carbapenem.

Carbapenem Side Effects and Dangers

There are several side effects that can occur after using carbapenems, including:

  • Dizzy
  • Headache
  • Nausea or vomiting
  • Diarrhea
  • Swelling, redness, or pain, at the injection site

Tell your doctor if the side effects mentioned above do not improve or if they get worse. Immediately see a doctor if you experience an allergic drug reaction or experience more serious side effects, such as:

  • Unusual fatigue
  • Severe cramping and abdominal pain
  • Ringing ears
  • Severe diarrhea or bloody diarrhea
  • seizures
  • Easy bruising
  • Jaundice

In addition, long-term use of this drug can increase the risk of fungal infections, which can be characterized by the appearance of candidiasis in the mouth or oral thrush .

Carbapenem Types and Trademarks

The following are the types of drugs that are included in the carbapenem antibiotic group, equipped with trademarks and doses that are adjusted for their intended use and the age of the patient:

Doripenem

Trademarks: Bizan, Daryaven, Dorbaz, Doripex, Doripenem, Doripenem Monohydrate, DRM, Novedor, Ribacter, Tironem

To find out the dosage and further information about this drug, please open the doripenem drug page .

Imipenem-cilastatin

Trademarks: Fiocilas, Imipex, Imiclast, Pelascap, Pelastin, Pencilas, Tienam, Timipen

To find out the dosage and more information about this drug, please visit the imipenem-cilastatin drug page .

Meropenem

Trademarks: Granem, Meropenem Trihydrate, Meropex, Ronem

To find out the dosage and more information about this drug, please visit the meropenem drug page .

Ertapenem

Trademark ertapenem : Invanz

Goal: Treat pneumonia, skin infections, urinary tract infections, or intra-abdominal infections

  • Adults: 1 gram, once daily by injection into a muscle (intramuscular/IM) for 7 days, or by intravenous infusion (intravenous/IV), for 30 minutes.
  • Children aged 3 months to 13 years: 0.015 gram/kgBB. The maximum dose is 1 gram per day.

Biapenem

biapenem trademark : -

Goal: Overcoming pneumonia, lung abscess, inflammation of the bladder (cystitis), respiratory and lung infections

  • Adult: 1.2 g, once daily in 2 divided doses by intravenous infusion (intravenous/IV), over 30–60 minutes.
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