Carbidopa is a drug used to treat the symptoms of Parkinson's disease, such as tremors and stiffness. To be effective, carbidopa must be combined with other Parkinson's disease medications , such as levodopa and entacapone.

Parkinson's disease is caused by a lack of dopamine in the brain. This condition will cause a series of symptoms, such as tremors , stiffness, and slow movement.

Carbidopa together with entacapone works by helping levodopa to enter the brain, which will then be broken down into dopamine . This working mechanism will help reduce complaints and symptoms of Parkinson's disease.

Carbidopa trademark: Stalevo

What is Carbidopa?

Group Antiparkinsonian
Category Prescription drugs
Benefits Relieves the symptoms of Parkinson's disease
Consumed by Adults
Carbidopa for pregnant and lactating women Category C: Studies on experimental animals show side effects on the fetus, but there are no controlled studies on pregnant women. The drug can only be used if the magnitude of the expected benefit exceeds the magnitude of the risk to the fetus. It is not yet known whether carbidopa can be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without first consulting your doctor.
Drug form Tablets

Warnings Before Consuming Carbidopa

Carbidopa cannot be consumed without a doctor 's prescription . In addition, there are several important things that must be considered before consuming carbidopa, namely:

  • Do not consume carbidopa if you are allergic to this drug.
  • Do not stop taking carbidopa without first consulting your doctor. The dose of carbidopa should be reduced gradually to avoid worsening of symptoms.
  • Do not consume alcoholic beverages during treatment with carbidopa.
  • Tell your doctor if you have a history of heart disease, liver disease, kidney disease, gastric ulcer, mental disorder, blood clotting disorder, sleep disorder, glaucoma , or seizures.
  • Avoid driving and doing activities that require alertness after consuming carbidopa, because this drug can cause drowsiness.
  • Tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • Tell the doctor if you plan to undergo dental treatment or surgery.
  • Immediately go to the doctor if there is an allergic reaction to the drug or an overdose occurs when consuming carbidopa.

Dosage and Administration of Carbidopa

To alleviate the symptoms of Parkinson's disease, 25 mg of carbidopa is combined with 100 mg of levodopa and 200 mg of entacapone. The dose is 1 tablet per drink, with a maximum dose of 8 tablets per day.

It should be noted that the dose above can vary for each patient, depending on the patient's condition and response to the drug.

How to Consume Carbidopa Correctly

Use carbidopa according to the instructions on the package and the doctor's instructions. Carbidopa can be consumed before or after meals.

Consume carbidopa regularly to get the maximum benefits of this drug. To help remember, take carbidopa at the same time each day.

Consumption of carbidopa by swallowing the drug tablet whole. Do not crush or chew first, because it can cause stains on the teeth.

Leave a long enough time between the consumption of carbidopa and food or supplements containing iron, because iron can reduce the amount of carbidopa absorbed by the body.

If you forget to take carbidopa, do it immediately so you remember if the break with the next schedule is not too close. When it's close, ignore it and don't double the dose.

Interactions of Carbidopa with Other Drugs

Do not consume carbidopa if within the previous 14 days you have used a monoamine oxidase inhibitor ( MAOI ) drug, such as isocarboxazid, because it can cause fatal side effects.

To avoid drug interaction effects, do not consume carbidopa together with the following drugs:

  • Antipsychotics
  • Antihypertensive
  • Antihistamines
  • Sleeping pills
  • Antianxiety
  • Muscle relaxation

Side Effects and Dangers of Carbidopa

Carbidopa rarely causes side effects. Usually, the side effects that appear are caused by the use of levodopa with other drugs. The side effects include:

  • Uncontrolled facial muscle movements, such as twitching eyes , chewing movements, or moving the tongue, without realizing it
  • Delirium, hallucinations , changes in mood and behavior, depression , or the appearance of suicidal thoughts
  • Falling asleep at the wrong time, such as while working, eating, or driving
  • Muscle stiffness, high fever, heart rhythm disorders , or fainting
  • The color of sweat, urine, and saliva changes to become darker
  • Worsening tremors
  • Nausea, vomiting, and severe diarrhea
  • Dizziness or headache
  • The tongue feels burning
  • Dry mouth
  • Stomachache
  • Convulsions

Immediately consult a doctor if you experience any of the above complaints or develop allergic reactions to drugs such as rash, swelling of the lips or eyelids, and difficulty breathing, after consuming carbidopa.

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