Cefadroxil is an antibiotic drug to treat bacterial infections in the throat, tonsils, skin, or urinary tract. In addition, this drug can also be used in the prevention of heart infections (endocarditis) prior to dental surgery or certain medical procedures in the respiratory tract.

Cefadroxil is a cephalosporin class of antibiotics. This drug works by inhibiting the formation of the bacterial cell wall, so the bacteria cannot survive, die, and the infection can be overcome.

Keep in mind, cefadroxil cannot be used to treat viral infections , such as the flu. This drug is available in the form of capsules, syrup, and may only be consumed according to a doctor's prescription.

Cefadroxil trademarks: Alxil, Biodroxil, Cefadroxil, Cefadroxil Monohydrate, Dexacef, Droxal, Droxefa, Lapicef, Lifadrox, Lostacef, Netfad 500, Renasistin, Roksicap, Staforin, Vocefa, Vocefa Forte, Yaricef

What is Cefadroxil

class Prescription drug
Category Cephalosporin class of antibiotics
Benefit Overcome bacterial infections of the skin and soft tissue, urinary tract, throat, or tonsils
Consumed by Adults and children aged ≥6 years
Cefadroxil for pregnant and lactating women Category B: Animal studies have not shown a risk to the fetus, but there are no controlled studies in pregnant women. Cefadroxil is absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.
Drug form Capsules and syrup

Precautions Before Taking Cefadroxil

Cefadroxil should not be taken carelessly. There are several things that need to be considered before using this drug, namely:

  • Tell your doctor about any allergies you have. Cefadroxil should not be taken by patients who are allergic to this drug or other cephalosporin class drugs, such as cefazolin .
  • Tell your doctor if you have or have ever had kidney disease , severe diarrhea, or ulcerative colitis .
  • Tell your doctor if you plan to get vaccinated with live vaccines, such as the BCG vaccine or typhoid vaccine , while having treatment with cefadroxil.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • Tell your doctor that you are taking cefadroxil if you plan to undergo special tests, such as a Coomb's test.
  • Immediately consult a doctor if you experience a drug allergic reaction , more serious side effects, or an overdose after taking cefadroxil.

Dosage and Instructions for Use of Cefadroxil

The dose of cefadroxil will be determined by your doctor based on your age, weight, or the condition you want to treat. In general, the following are the dosages of cefadroxil:

Condition: Pharyngitis or tonsillitis due to Streptococcus infection

  • Adult: 1,000 mg once daily or 500 mg twice daily for 10 days.
  • Children with body weight (BW) <40 kg: 30 mg/kgBW per day divided into 1-2 times, for 10 days.

Condition: Skin and soft tissue infection or urinary tract infection

  • Adult: 1000–2000 mg daily in 1–2 divided doses.
  • Children aged ≥6 years with a weight <40 kg: 30 mg/kg per day divided into 1-2 doses.

Condition: Prevention of endocarditis after surgical procedures on teeth or special medical procedures on the respiratory tract

  • Adult: 2,000 mg per day, consumed 1 hour before the patient has surgery on the teeth or special medical procedures on the respiratory tract.
  • Children: 50 mg/kgBB per day, consumed 1 hour before the patient has dental surgery or special medical procedures on the respiratory tract. Dosage should not exceed 2,000 mg.

How to Take Cefadroxil Correctly

Follow the doctor 's advice and read the information listed on the drug packaging label before taking cefadroxil. This medicine can be taken before or after meals. However, to avoid heartburn, cefadroxil should be taken with food.

Swallow cefadroxil capsules whole with a glass of water. For cefadroxil in syrup form, shake the bottle before use. Use the measuring spoon contained in the package so that the dose consumed is correct.

Take cefadroxil regularly at the same time every day for maximum treatment effect. If you forget to take this drug, consume it immediately if the break with the next consumption schedule is not too close. If it is close, ignore it and do not double the dose.

Make sure to finish all the cefadroxil prescribed by the doctor even if the symptoms have improved, so that the infection is completely cured.

Store cefdroxil capsules and syrup in a closed container in a cool room. Protect this drug from direct sunlight and keep the drug out of the reach of children.

Interactions of Cefadroxil with Other Drugs

The use of cefadroxil with other drugs can cause interactions between drugs. These interactions can take the form of:

  • Increased risk of kidney damage from aminoglycoside antibiotics , such as neomycin or gentamicin
  • Increased risk of bleeding when used with blood thinners, such as warfarin , aspirin, or clopidogrel
  • Increased risk of opposite effects, thereby reducing the effectiveness of each drug when taken with erythromycin , chloramphenicol, sulfonamides, or tetracyclines
  • Increased blood levels of cefadroxil when used with probenecid
  • Decreased effectiveness of cefadroxil when used with cholestyramine
  • Decreased effectiveness of live vaccines, such as the BCG vaccine or typhoid vaccine

Cefadroxil Side Effects and Dangers

Some of the side effects that may appear after consuming cefadroxil are:

  • Nausea or vomiting
  • Stomach ache
  • Diarrhea

Check with your doctor if these side effects don't go away or get worse.

Immediately see a doctor if you experience an allergic drug reaction or more serious side effects, such as:

  • Liver disease that can be characterized by symptoms such as loss of appetite, jaundice , dark urine
  • An infectious disease that can be characterized by symptoms such as a sore throat or fever that does not go away
  • C. difficile infection in the digestive tract which can be characterized by symptoms such as severe diarrhea, abdominal pain or cramps , or bloody stools

In addition, long-term use of cefadroxil can cause a fungal infection which can be characterized by the appearance of a white rash on the tongue or abnormal vaginal discharge.

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