Cefixime is an antibiotic drug for treating respiratory tract infections, throat and tonsil infections, ear infections, urinary tract infections, and sexually transmitted infections, such as gonorrhea. 

Cefixime belongs to   the third generation cephalosporin antibiotic class. This drug works by inhibiting the formation of the bacterial cell wall. That way, the bacteria cannot survive and the infection can be overcome. Cefixime cannot be used to treat infections caused by viruses, such as the flu.

Cefixime trademarks : Anfix, Cefixime Trihydrate, Cefacef, Cefarox, Cefila, Cefixstar, Cefspan, Ceptic, Cerafix, Fixacep, Fixam, Fixatic, Helixim, Lanfix, Inbacef, Lanfix DS, Nixaven, Oracef, Profim, Simcef, Sporetik, Starcef, Trixim 200, Tocef, Ximecef, Yafix

What is Cefixime

class Prescription drug
Category Cephalosporin class of antibiotics
Benefit Treating bacterial infections
Consumed by Adults and children
Cefixime for pregnant and lactating women


Category B: Animal studies have shown no risk to the fetus, but there have been no controlled studies in pregnant women.

It is not yet known whether cefixime can be absorbed into breast milk or not. If you are breastfeeding, do not use this medication without consulting your doctor.

Drug form Tablets, chewable tablets , capsules, caplets, and syrups

Precautions Before Taking Cefixime

Cefixime should only be used according to a doctor's prescription. The following are things you need to pay attention to before taking cefixime:

  • Do not take cefixime if you are allergic to it or to other cephalosporin class antibiotics, such as cefotaxim . Always tell your doctor about any allergies you have.
  • Tell your doctor if you have or currently have  kidney disease or a disease of the digestive tract, such as colitis .
  • Tell your doctor if during treatment with cefixime you plan to immunize with a live vaccine, such as  the typhoid vaccine .
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking any other medicines, including supplements, or herbal products.
  • See your doctor right away if you have  an allergic reaction to medication , serious side effects, or an overdose after taking cefixime.

Dosage and Rules for Use Cefixime

Dosage and rules for using cefixime vary for each patient. The doctor will give the dose and determine the duration of treatment according to the condition and age of the patient.

In general, the following are the doses for bacterial infections:

  • Adult: 200–400 mg, per day, in 1–2 divided doses, for 7–14 days.
  • Children aged over 6 months to 10 years with body weight <50 kg: 8 mg/kg, per day, which can be divided into 1-2 doses.

How to Take Cefixime Correctly

Use cefixime as recommended by  the doctor  and don't forget to read the information on the drug packaging. Do not increase or decrease the dose, and do not use the drug for more than the recommended time.

Cafixime tablets, caplets, or capsules can be taken before or after meals. Take cefixime tablets, caplets or capsules with a glass of water. Swallow the tablets, caplets, or capsules whole, do not crush or chew them.

If you are taking cefixime in syrup form, shake the bottle before drinking. Use the measuring spoon that is available in the medicine package so that the dosage is more precise.

For those of you who take cefixime in the form of a chewable tablet, the tablet must be chewed first and not swallowed whole.

For effective treatment, take cefixime at the same time every day. Make sure there is sufficient time between one dose and the next. Do not stop treatment prematurely, even though complaints or symptoms have improved.

If you forget to take cefixime, take it as soon as you remember. However, if it is near the time of your next dose, ignore the missed dose. Do not double the dose of cefixime to make up for a missed dose, unless directed by your doctor.

Store cefixime at room temperature, in a dry place, away from direct sunlight and out of reach of children.

Interactions of Cefixime with Other Drugs

There are several interactions that can occur if cefixime is used together with other drugs, including:

  • Increased risk of bleeding if used with anticoagulant drugs , such as warfarin
  • Increased cefixime levels when used with nifedipine or probenecid
  • Increased levels of carbamazepine in the blood
  • Decreased effectiveness of vaccines derived from live bacteria, such as BCG vaccine, typhoid vaccine, or cholera vaccine

Cefixime Side Effects and Dangers

Side effects that may arise after consuming cefixime are:

  • Headache or dizziness
  • Nausea or vomiting
  • Abdominal pain or bloating
  • Diarrhea

Check with your doctor if the side effects above do not subside or get worse. Immediately see a doctor if you have an allergic reaction to the drug or a more serious side effect, such as:

  • Severe stomach pain, nausea and vomiting that doesn't go away, or jaundice
  • An infectious disease that can be characterized by symptoms such as fever or sore throat that does not go away
  • C. difficile infection which can be characterized by symptoms such as diarrhea that doesn't stop, stomach cramps, or slimy or bloody stools .

In addition, long-term use of cefixime can increase the risk of fungal infections which can be characterized by the appearance of white rashes such as thrush in the mouth and tongue or abnormal vaginal discharge.

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