Skip to content


Chlorhexidine is a liquid medicine to maintain oral health and treat canker sores, gingivitis, or oral candidiasis . Chlorhexidine is also used to clean wounds or areas to be injected or operated on .

Chlorhexidine is an antiseptic and antibacterial. This drug works by killing and preventing the growth of bacteria. As an antiseptic. chlorhexidine is also used to sterilize surgical equipment.

Chlorhexidine trademarks: Hu Fu Ling, Minosep, Perio Kin Spray

What is Chlorhexidine

class Free medicine
Category Antiseptic and antibacterial
Benefit Treat thrush, oral candidiasis , or inflammation of the gums (gingivitis), maintain oral hygiene, or be an antiseptic or disinfectant
Used by Adults and children 12 years old
Chlorhexidine for pregnant and lactating women Category B for use in the throat , mouth , or skin : Animal studies have not demonstrated a risk to the fetus, but there have been no controlled studies in pregnant women.

It is not known whether chlorhexidine is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor.

Drug form Mouthwash, external medicine liquid, spray for the gums and mouth

Precautions Before Using Chlorhexidine

There are several things you need to pay attention to before using chlorhexidine, namely:

  • Do not use chlorhexidine if you are allergic to this drug.
  • Tell your doctor if you are wearing dentures or dental veneers , or have permanent fillings.
  • Tell your doctor about your medical history, especially if you have periodontitis .
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Be careful when using chlorhexidine and do not get it in contact with or enter the eyes, genitals, or If accidentally exposed to these parts, rinse immediately with clean water.
  • Avoid using external liquid chlorhexidine on open wounds, especially large or deep ones, unless directed by a doctor.
  • Immediately see a doctor if you experience an allergic reaction to the drug or a more serious side effect after using chlorhexidine.

Dosage and Rules for Use of Chlorhexidine

The following is a general dosage for chlorhexidine based on the purpose of use and the form of the drug:

Purpose: Treat oral thrush or candidiasis, or maintain oral hygiene

  • Form of drug: Spray chlorhexidine digluconate 0.2%
    Adults: Spray sufficiently, 2 times a day. Maximum dose of 12 sprays, 2 times a day.
  • Form of medication: Mouthwash chlorhexidine digluconate 0.2%
    Adults and children ≥12 years: Gargle with 10 ml of medication for 1 minute. If using medicine to clean dentures, soak dentures in mouthwash for 15 minutes, 2 times a day.

Goal: Treat and prevent gingivitis

  • Drug form: Spray chlorhexidine digluconate 0.2%
    Adult: Spray as needed 2 times a day, for 1 month. Maximum dose of 12 sprays, 2 times a day.
  • Form of drug: Mouthwash 0.2%
    Adults and children aged ≥12 years: Gargle with 10 ml of the drug, for 60 seconds.

Purpose: Cleaning wounds
Use just enough to clean wounds or burns.

How to use Chlorhexidine properly

Chlorhexidine to clean the operating area or wounds, especially large or deep wounds, will be given directly by a doctor or medical personnel under the supervision of a doctor. Follow your doctor's instructions if you are prescribed this liquid for home use.

Chlorhexidine for the mouth can be used independently. Follow your doctor 's advice and read the information on the package before starting to use this medicine. Do not increase or decrease the dose and frequency of use of chlorhexidine.

For mouthwash or spray , make sure to rinse your mouth after brushing your teeth. Gargle according to the doctor's instructions. Do not eat or drink for several hours after using the mouthwash.

Do not swallow chlorhexidine or mix it with water before use. Discard chlorhexidine after gargling.

Store chlorhexidine at room temperature away from direct sunlight, and keep the drug out of reach of children.

Chlorhexidine Interactions with Other Drugs

As long as it is used according to the rules of use, chlorhexidine usually does not cause certain interactions when used with other drugs. However, as a precaution, tell your doctor if you are using other medicines, including supplements and herbal products.

Chlorhexidine Side Effects and Dangers

Chlorhexidine used on the skin usually does not cause side effects. However, using too much chlorhexidine or on body folds can cause side effects in the form of skin redness, itching or irritation.

Meanwhile, some of the side effects that can occur after using chlorhexidine for oral use are:

  • Dry mouth
  • Mild burning or tingling sensation in the mouth that appears suddenly
  • Irritation in mouth and throat
  • Changes in the taste of food or drink
  • An increase in the amount of hardened plaque (tartar) on the teeth
  • The color of the medicine imprints on the tongue or teeth

Check with your doctor if the side effects you experience don't improve or get worse. Stop using chlorhexidine and see a doctor immediately if you have an allergic drug reaction or more serious side effects, such as:

  • The inside of the mouth is peeling
  • Spreading skin rash
  • Difficulty swallowing
  • Severe sore throat
  • Headache
  • Nausea or vomiting
  • Fever
Back to blog