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Chlorzoxazone  is a drug to treat pain due to muscle cramps or tension . This medication is usually used for muscle cramps that accompany musculoskeletal conditions, such as sciatica or cervical spondylosis.

Chlorzoxazone acts on the central nervous system to relax tense muscles so that it can reduce pain and make movement more flexible. In order for the maximum effect of treatment, the use of this drug needs to be accompanied by physiotherapy and adequate rest.

Chlorzoxazone trademark: Solaxin

What is Chlorzoxazone

class Prescription drugs
Category muscle relaxant
Benefit Overcoming muscle cramps, for example in sciatica or cervical spondylosis
Consumed by Mature
Chlorzoxazone for pregnant and lactating women Category C: There is not enough evidence from animal or human studies to explain the safety of the drug in pregnant women or the fetus.

Therefore, this drug should not be consumed by pregnant women, unless advised by a doctor.

It is not known whether chlorzoxazone is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without your doctor's approval.

Drug form Tablet

Precautions Before Taking Chlorzoxazone

Chlorzoxazone should not be used carelessly. There are several things that must be considered before using this drug, including:

  • Do not take chlorzoxazone if you are allergic to this drug. Tell your doctor about any allergies you have.
  • Avoid consuming alcoholic beverages while undergoing treatment with chlorzoxazone.
  • Do not drive or do other activities that require alertness after taking chlorzoxazone, as this medicine can cause dizziness and drowsiness.
  • Tell your doctor if you have had or currently have liver disease or porphyria .
  • Tell your doctor about taking this drug if you plan to have dental treatment or surgery.
  • Inform your doctor if you are taking certain drugs, supplements or herbal products, to anticipate interactions between drugs.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See your doctor immediately if you have an allergic reaction to the drug or a more serious side effect after taking chlorzoxazone.

Dosage and Rules for Use Chlorzoxazone

The initial dose of chlorzoxazone for pain relief from muscle cramps in adults is 500 mg 3–4 times daily. The dose may be reduced gradually to 250 mg 3–4 times daily when the pain is relieved. The maximum dose is 750 mg, 3–4 times daily.

How to Take Chlorzoxazone Correctly

Always follow the doctor 's recommendations and read the instructions for use on the packaging before taking chlorzoxazone. Do not use the drug for longer than the doctor recommends.

Chlorzoxazone can be taken before or after meals. Swallow the medicine with the help of water. Do not increase or decrease the dose of the drug without the doctor's approval.

If you forget to take chlorzoxazone, take this medicine as soon as you remember. However, if your next dose is near, ignore the missed dose and don't double the next dose.

Carry out routine controls to the doctor while undergoing treatment with this drug so that your body's condition and response to treatment are always monitored. In severe conditions, you also need to do routine physiotherapy.

This drug has the potential to cause serious side effects on the liver. As a precaution, your doctor may ask you to do liver function tests, especially if chlorzoxazone is taken in the long term.

Store chlorzoxazone indoors at room temperature and protected from direct sunlight, and out of reach of children.

Interaction of Chlorzoxazone with Other Drugs

The use of chlorzoxazone together with other drugs can cause drug interactions, including:

  • Increased drowsiness, dizziness, or difficulty concentrating when used with sleeping pills, benzodiazepines , or barbiturates
  • Increased blood levels of chlorzoxazone when used with disulfiram or isoniazid

Chlorzoxazone Side Effects and Dangers

Consumption of chlorzoxazone can cause side effects in the form of changes in the color of urine to orange or purplish red. These side effects are not dangerous and will disappear if the consumption of the drug is stopped.

However, there are some other side effects that may occur after taking chlorzoxazone, including:

  • Diarrhea
  • Nauseous
  • Vomit
  • Drowsiness
  • Dizzy
  • Tired
  • Gastric pains
  • Headache

Check with your doctor if the side effects above don't go away or get worse. See your doctor immediately if you have an allergic reaction to the drug or a more serious side effect, such as:

  • Liver disturbances, which may be characterized by dark urine, nausea or vomiting that doesn't stop, abdominal pain, or yellowing of the skin and eyes ( jaundice )
  • Feeling lightheaded or like you're going to pass out
  • Rash, itching, or redness on the skin
  • Severe sleepiness or confusion
  • Unusual bruising or bleeding
  • Bleeding in the digestive tract , which can be marked by black stools like asphalt, or vomit with dregs like coffee grounds
  • Symptoms of infection, which can include a sore throat or fever that doesn't get better
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