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Cinnarizine is a drug to treat vertigo, ringing in the ears (tinnitus), nystagmus, and vomiting and nausea caused by disorders of the inner ear, such as Meniere's disease. In addition, this drug is also used to prevent motion sickness.

Cinnarizine works by blocking excessive stimulation in the inner ear that can cause dizziness and nausea. This drug can also cause drowsiness so that it can distract a person from these stimuli, including during travel.

Cinnarizine also acts as a calcium antagonist that can dilate blood vessels and increase blood flow, both in the inner ear and elsewhere in the body. Therefore, cinnarizine can also be used to treat blood circulation disorders in the brain, or in the periphery (hands or feet).

Cinnarizine trademarks : Brazine, Goron, Merron 25, Narmig, Nariz, Perifas, Stugeron, Vertizine

What is Cinnarizine

class Prescription drugs
Category antivertigo
Benefit Overcome vertigo, ringing in the ears (tinnitus), nystagmus , and vomiting and nausea caused by disorders of the inner ear, such as Meniere's disease

Prevent motion sickness

Consumed by Adults and children
Cinnarizine for pregnant and lactating women Category B: Animal studies have not demonstrated a risk to the fetus, but there have been no controlled studies in pregnant women.

If you are pregnant, you should consult your doctor about using this drug.

It is not known whether cinnarizine can be absorbed into breast milk or not. However, this drug is not recommended for use by breastfeeding mothers.

Drug form Caplets and tablets

Precautions Before Taking Cinnarizine

Cinnarizine should only be used with a doctor's prescription. Before taking this drug, you need to pay attention to the following things:

  • Do not take cinnarizine if you are allergic to this drug. Tell your doctor about any allergies you have.
  • Tell your doctor if you have had or currently have porphyria , liver disease, Parkinson's disease, kidney disease, benign prostate enlargement , difficulty urinating, glaucoma , epilepsy, seizures, or intestinal obstruction .
  • Tell your doctor that you are taking or have recently finished taking cinnarizine if you are planning to have an allergy test . Stop using the drug at least 4 days before you have the test.
  • Inform your doctor if you are taking other medications, including supplements and herbal products, to anticipate drug interactions.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Do not consume alcoholic beverages while on treatment with cinnarizine.
  • Do not immediately drive a vehicle or do other activities that require alertness after taking cinnarizine, as this medicine may cause dizziness or drowsiness.
  • Consult your doctor about using cinnarizine in children, because this drug can cause side effects.
  • See your doctor immediately if you have an allergic reaction to a drug or overdose after taking cinnarizine

Dosage and Rules for Use Cinnarizine

The dose of cinnarizine given by the doctor depends on the condition and age of the patient. Here is the explanation:

Goal: To treat inner ear disorders, such as dizziness, vertigo, tinnitus , nystagmus, nausea, or vomiting

  • Adults and children >12 years of age: 75 mg, once daily or 25 mg, 3 times daily.

Goal: Prevent motion sickness

  • Adults and children >12 years: 25 mg, should be taken at least 30 minutes before travel. Doses may be repeated every 6 hours if necessary.
  • Children 6–12 years: 12.5 mg, should be taken at least 30 minutes before travel, dose may be repeated every 6 hours if necessary.

Goal: Treat symptoms due to impaired cerebral blood circulation, including forgetfulness and difficulty concentrating

  • Adult: 75 mg, once daily or 25 mg, 3 times daily.

Goal: Overcoming peripheral blood circulation disorders

  • Adult: 50–75 mg, 2–3 times daily. The maximum dose is 225 mg per day.

How to Take Cinnarizine Correctly

Follow the doctor 's advice and read the information listed on the medicine package before taking cinnarizine. Do not increase or decrease the dose without consulting your doctor.

Cinnarizine can be taken with food or immediately after a meal. Cinnarizine tablets can be sucked or chewed freshly swallowed, or swallowed with the help of a glass of water.

Take cinnarizine regularly at the same time each day. If you forget to take cinnarizine, take this medicine immediately if it is not close to your next scheduled consumption. If it is close, ignore the missed dose and do not double the next dose.

Store cinnarizine at room temperature and protected from direct sunlight, and keep out of reach of children.

Cinnarizine Interactions with Other Drugs

The use of cinnarizine with barbiturate class drugs, opioid analgesics , antipsychotics, antianxiety , or tricyclic antidepressants , can cause interactions between drugs in the form of increased drowsiness.

Side Effects and Dangers of Cinnarizine

Some of the side effects that can occur after consuming cinnarizine are:

  • Daytime sleepiness
  • Nausea or vomiting
  • Weight gain
  • Headache
  • Heartburn
  • Dry mouth
  • Fatigue

Check with a doctor if the complaints mentioned above do not go away or get worse. See your doctor right away if you have an allergic reaction to a drug or a more serious side effect, such as:

  • Body movements become slow or uncontrolled movements appear, especially in the elderly
  • Muscle stiffness, twitching, shaking, or tremors
  • Liver disorders, characterized by jaundice and dark urine
  • Joint pain accompanied by a red rash on areas of the body that are exposed to the sun, such as the arms, cheeks, and nose
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