Clebopride is a drug to stop nausea and vomiting due to a number of conditions, such as stomach acid, chemotherapy, radiotherapy, or postoperative anesthesia. This drug is available in tablet form and should only be used as prescribed by a doctor.

Clebopride works in two ways to treat nausea and vomiting. First, these drugs block the stimulation of nausea and vomiting that comes directly from the brain. In addition, clebopride can speed up the emptying of the stomach into the intestines. With this way of working, nausea and the urge to vomit is reduced.

Clebopride -

Clebopride trademark: Clast

What is Clebopride

class Antiemetic
Category Prescription drugs
Benefit Relieves nausea and vomiting
Used by Child to adult
Clebopride for pregnant and lactating women  Category C: There is insufficient evidence from animal or human studies to demonstrate the safety of the drug in pregnant women and the fetus. Therefore, this drug should not be consumed by pregnant women, unless the doctor recommends it. Clebopride is not yet known to be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without your doctor's approval.
Form Tablet

 Precautions Before Taking Clebopride

Clebopride should not be used carelessly. Some things you need to pay attention to before taking cleboprid are:

  • Do not take clebopride if you are allergic to this drug. Always tell your doctor about any allergies you have.
  • Tell your doctor if you have gastrointestinal bleeding, intestinal obstruction , or pheochromocytoma . Clebopride should not be used by patients with these conditions.
  • Tell your doctor if you have a history of kidney disease, Parkinson's disease , epilepsy, tardive dyskinesia , or depression .
  • Do not drive or do other activities that require alertness while taking clebopride, because this drug can cause dizziness and drowsiness.
  • Do not consume alcoholic beverages while on treatment with clebopride, because alcohol can increase the risk of side effects.
  • Tell your doctor if you are taking other medications, including supplements and herbal products, to anticipate drug interactions.
  • Inform your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Discuss with your doctor first if you plan to give clebopride to children or the elderly.
  • Immediately consult a doctor if you experience a drug allergic reaction or serious side effects after taking clebopride.

Dosage and Rules for Use Clebopride

Clebopride is available in the form of clebopride malate. The dose of clebopride between patients depends on their age or weight. Following are details of the dosage of clebopride to treat nausea and vomiting :

  • Adults: 500 mcg, 3 times daily
  • Children : 15–20 mcg/kg, 3 times a day

How to Take Clebopride Properly

Follow the doctor 's recommendations and read the instructions for use on the packaging before taking clebopride. Do not increase or decrease the dose taken without the doctor's approval.

Take clebopride on an empty stomach, ideally 30 minutes before a meal. Swallow the clebopride tablets with plain water.

If you forget to take clebopride, take this drug as soon as you remember. However, if you only remember when your next scheduled time is near, ignore the missed dose and do not double up on the next dose.

Store clebopride in a dry, cool place away from direct sunlight, and out of reach of children.

Interactions of Clebopride with Other Drugs

If used together, clebopride can affect the body's absorption of other drugs. In addition, there are several interaction effects that can occur if clebopride is used with certain drugs, including:

  • Increased risk of extrapyramidal syndrome, such as rigidity, slowed movements, or tremors, when used with chlorpromazine or haloperidol
  • Increased risk of lithium side effects
  • Reduced effectiveness of clebopride when used with opioid pain relievers or anticholinergic drugs, such as atropine
  • Increased effect of drowsiness when used simultaneously with sleeping pills, sedatives , or alcohol

Clebopride Side Effects and Dangers

There are several side effects that can occur after taking clebopride, including:

  • Headache
  • Drowsiness
  • Diarrhea
  • Dizzy
  • Discharge from the breast (galactorrhea)

Check with your doctor if the side effects above don't go away or get worse. Stop using clebopride and see a doctor immediately if you have an allergic reaction to the drug or serious side effects, such as:

  • Malignant neuroleptic syndrome, which may be characterized by muscle rigidity, hyperthermia , and mental changes
  • Depression, which can be characterized by a deep feeling of sadness and loss of interest in activities
  • Can not be silent
  • Movement that presents itself, whether in the face, hands, or feet
Back to blog