Colestipol

Colestipol

Colestipol is a drug to lower bad cholesterol or low-density lipoprotein (LDL). By lowering bad cholesterol levels, the risk of heart attack and stroke can also be lowered.

Colestipol belongs to a class of bile acid sequestrant drugs or bile acid binders. This drug works by removing bile acids from the body, so that the liver can produce more bile acids by using cholesterol in the blood.

To reduce bad cholesterol levels, drug consumption must be combined with healthy lifestyle settings, for example by exercising regularly or reducing high-fat foods.

Colestipol trademark:-

What is Colestipol

class Prescription drug
Category Bile acid binder
Benefit Helps lower bad cholesterol levels
Consumed by Mature
Colestipol for pregnant and lactating women  Category C:  Animal studies have shown an adverse effect on the fetus, but there have been no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether colestipol is absorbed into breast milk or not. Breastfeeding mothers are advised to consult a doctor before using this medicine.

Drug form Powder and tablets

Warning Before Consuming Colestipol

Before taking this drug, you need to pay attention to the following things:

  • Do not use colestipol if you are allergic to this drug. Tell your doctor about any history of allergies you have.
  • Tell your doctor if you have or are currently suffering from constipation , liver disease, difficulty swallowing , thyroid disease, hemorrhoids , blood clotting disorder, gallstones , stomach disease, intestinal obstruction , or kidney disease .
  • Tell your doctor if you have had surgery on your stomach, intestines, or digestive tract.
  • Tell your doctor before taking colestipol if you have phenylketonuria . Some colestipol products may contain phenylalanine.
  • Colestipol should not be used in patients under 18 years of age.
  • Tell your doctor if you are taking any medications, supplements, or herbal products. Colestipol can affect the absorption of folic acid and fat-soluble vitamins, such as  vitamins A , D, E, and K.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Immediately see a doctor if an allergic drug reaction or overdose occurs after using colestipol.

Dosage and Rules for Use Colestipol

Colestipol is only given based on doctor's advice. The following is a common dose for using colestipol for high cholesterol to lower bad cholesterol ( LDL ) levels:

  • Tablet form. The
    dose is 2 grams, 1-2 times a day, then increase the dose by 2 grams after 1-2 months of treatment. The maintenance dose is 2–16 grams per day, once daily or divided into several doses.
  • Powder form. The
    dose is 5 grams, 1–2 times a day, then increase the dose by 5 grams after 1 month of treatment. The maximum dose is 30 grams per day, divided into 1-2 doses.

How to Take Colestipol Correctly

Follow the doctor 's recommendations and read the information printed on the drug packaging before taking colestipol. Do not reduce or increase your dose without consulting your doctor first.

Colestipol can be taken before or after meals. Try to take colestipol at the same time every day for maximum treatment.

Swallow colestipol tablets whole with the help of a glass of water. Do not chew or crush the tablets

Dissolve colestipol powder into drinks or food. This drug should not be consumed in dry form. Consume food or drink that has been mixed with the drug until it runs out, in order to get the right dose.

Immediately swallow the colestipol solution without gargling or letting it sit in your mouth, as this drug can damage your teeth if left too long.

If you are taking other drugs, take them at least 1 hour before or 4–6 hours after taking colestipol.

During treatment with colestipol, your doctor may ask you to have regular blood tests . Follow the examination schedule that has been determined by the doctor.

If you forget to take colestipol, it is advisable to take it immediately if the break with the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Store colestipol in a dry place and avoid exposure to direct sunlight. Keep this drug out of reach of children.

Colestipol Interactions with Other Drugs

Colestipol may inhibit the absorption of the following medicines when taken together:

  • Folic acid
  • Phosphate Supplements
  • Tetracycline
  • Penicillin G
  • Hydrochlorothiazide
  • Furosemide
  • Gemfibrozil
  • Fat-soluble vitamins, such as vitamin D or A
  • Digoxin
  • Mycophenolic acid
  • Propranolol

Colestipol Side Effects and Dangers

Some of the side effects that can occur after taking colestipol are:

  • Stomach ache
  • Bloated
  • Constipation or diarrhea
  • Nausea or vomiting
  • Headache
  • Loss of appetite
  • Bloody stools or black stools
  • Easy bruising or unusual bleeding

Check with your doctor if the side effects above do not subside or get worse. You should also see a doctor immediately if you experience an allergic drug reaction after taking colestipol.

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