Dapagliflozin is a drug to lower blood sugar levels in type 2 diabetes sufferers. This drug can also be used to reduce the risk of heart failure in type 2 diabetes patients who suffer from heart problems.

Dapagliflozin works by increasing the disposal of blood sugar through urine. This way of working can also increase the elimination of body fluids so that dapgliflozin can be used to treat conditions associated with excess body fluids.

Dapagliflozin may also be used in patients with heart failure and kidney disease who do not have type 2 diabetes. Dapagliflozin may reduce the risk of hospitalization, further decline in kidney function , or death from heart disease in patients with these conditions.

Dapagliflozin trademarks: Diaglifozmet XR , Forxiga, Xigduo XR

What is Dapagliflozin

class Prescription drug
Category Antidiabetic
Benefit Overcoming type 2 diabetes
Consumed by Mature
Dapagliflozin for pregnant and lactating women Category D:  There is evidence that the ingredients pose a risk to the human fetus, but the benefits may outweigh the risks, for example in treating a life-threatening situation. It is not known whether dapagliflozin is absorbed into breast milk. However, this drug is not recommended for nursing mothers. Do not use this medicine without consulting your doctor first.
Drug form Film-coated tablets

Precautions Before Taking Dapagliflozin

There are several things you need to pay attention to before using dapgliflozin, namely:

  • Do not take dapagliflozin if you are allergic to this drug.
  • Dapagliflozin cannot be used to treat high blood sugar levels in people with type 1 diabetes or diabetic ketoacidosis .
  • Tell your doctor if you have or currently have liver disease , hypotension , kidney disease, alcoholism , urinary tract infection, yeast infection of the genitals ( candidiasis ), difficulty urinating, or pancreatic disease .
  • Tell your doctor if you are dehydrated or have any conditions that increase your risk of becoming dehydrated, such as vomiting or diarrhea, both before and while taking dapagliflozin.
  • Tell your doctor if you have had, are currently on, or plan to have dialysis , pancreatic surgery, or a low-salt diet .
  • Inform your doctor if you are pregnant or breastfeeding. Also tell if you may become pregnant or want to plan a pregnancy, either before or while taking dapagliflozin.
  • Tell your doctor if you will or are taking any other medications, including supplements and herbal remedies, to anticipate drug interactions.
  • Immediately see a doctor if you experience a drug allergic reaction or overdose after taking dapagliflozin.

Dosage and Instructions for Use of Dapagliflozin

The following is the general dosage of dapgliflozin based on the patient's condition:

Condition: Type 2 diabetes

  • 5 mg 1 time a day. Doctors can increase the dose to 10 mg if blood sugar levels are still too high.

Condition: Chronic kidney disease or heart failure , with or without type 2 diabetes

  • 10 mg 1 time a day.

How to Take Dapagliflozin Correctly

Follow the doctor 's advice and read the instructions on the medicine package before taking dapagliflozin.

Dapagliflozin can be taken before or after meals. Swallow dapagliflozin tablets whole with the help of water. This medicine should be taken in the morning.

If you forget to take dapagliflozin, take this medicine immediately if the break with the next consumption schedule is not too close. When it is close, ignore and do not double the dose.

While undergoing treatment with dapgliflozin, the patient will be asked to carry out tests to monitor blood sugar levels and see the effectiveness of the therapy.

Dapagliflozin cannot cure type 2 diabetes. For maximum treatment results, the use of dapagliflozin must be accompanied by the adoption of a healthy diet and regular exercise according to the needs and abilities of the patient.

Store dapagliflozin in a dry, room temperature place away from direct sunlight. Keep out of reach of children.

Dapagliflozin Interactions with Other Drugs

Dapagliflozin can cause interactions between drugs when used with other drugs, namely:

  • Increased risk of dehydration and hypotension when used with thiazide or loop diuretics
  • Increased risk of developing low blood sugar levels if used with insulin or sulfonylurea antidiabetic drugs

Dapagliflozin Side Effects and Dangers

There are several side effects that can occur after taking dapagliflozin, including:

  • Dizzy
  • Frequent urination
  • Head feels light as if going to faint
  • Easy thirst

Check with your doctor if these side effects do not improve or get worse. Immediately go to the doctor if you experience a drug allergic reaction which is characterized by swelling in the face, a rash appears, or difficulty breathing.

Dapagliflozin rarely causes low blood sugar levels (hypoglycemia). However, the risk of developing hypoglycemia is greater if this drug is used in combination with other antidiabetic drugs.

In addition, there are some serious side effects that can occur due to the use of dapagliflozin. See a doctor immediately if you experience the following side effects:

  • Nauseous
  • Vomit
  • Unusual tired
  • Severe stomach ache
  • Symptoms of a urinary tract infection , which can be characterized by pain when urinating, cloudy or bloody urine
  • Leucorrhoea that is white or yellowish in color, as well as itching or an unpleasant odor in the vagina
  • Itching, redness, rash, or swelling on the penis, smelly discharge from the penis, or pain in the skin around the penis
  • Fast heart rate
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