Dexketoprofen is a medication used to relieve mild to moderate pain caused by certain conditions, such as sprains, toothaches, or menstrual pain . This drug belongs to the class of non-steroidal anti-inflammatory drugs.

Dexketoprofen works by inhibiting the production of prostaglandins . When an injury or injury occurs, prostaglandin levels can increase and cause symptoms of inflammation, such as pain and swelling.


By inhibiting the production of prostaglandins, the symptoms of inflammation, such as pain and swelling, will also subside. Dexketoprofen should not be used carelessly and must be according to a doctor's prescription.

Dexketoprofen trademarks: Dexketoprofen Trometamol, Dextofen, Cool, Tofedex, Tordex, Voxib

What is Dexketoprofen

class Prescription drug
Category Non-steroidal anti-inflammatory drugs ( NSAIDs )
Benefit Relieves pain symptoms of mild to moderate intensity
Used by Mature
Dexketoprofen for pregnant and lactating women


Category N: Not yet categorized.

It is not known whether Dexketoprofen is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Tablets and injections

Warning Before Using Dexketoprofen

Dexketoprofen should only be used as prescribed by a doctor. Here are some things you need to pay attention to before using dexketoprofen:

  • Do not use dexketoprofen if you are allergic to this medicine or to other NSAIDs, such as ketoprofen . Tell your doctor about any allergies you have.
  • Tell your doctor if you have or have had stomach ulcers , kidney disease, asthma , liver disease, duodenal ulcers , gastrointestinal bleeding, heart disease, or inflammatory bowel disease , such as Crohn's disease or ulcerative colitis.
  • Tell your doctor if you have hypertension , lupus , a blood clotting disorder, diabetes , or high cholesterol .
  • Tell your doctor if you are taking certain medications, herbal products, or supplements.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See a doctor immediately if you have an allergic drug reaction, serious side effects, or an overdose after using dexketoprofen.

Dosage and Rules for Using Dexketoprofen

The dose of dexketoprofen will be given by the doctor according to the condition you want to treat and the form of the drug. The following is a general dosage of dexketoprofen for treating pain based on the form of the drug:

  • Form: Tablet
    Dose 12.5 mg every 4–6 hours or 25 mg every 8 hours. The maximum dose is 75 mg per day.
  • Form: Injectable
    Dosage 50 mg every 8-12 hours. If needed, the injection will be given again after 6 hours. The maximum dose is 150 mg per day.

Please note, injection of dexketoprofen is done through a vein (intravenous/IV) or through a muscle (intramuscular/IM) by a doctor or medical officer under the supervision of a doctor.

How to Use Dexketoprofen Properly

Follow the doctor 's recommendations and read the instructions for use on the packaging when using dexketoprofen. Dexketoprofen injection should only be given directly by a doctor or medical officer under the supervision of a doctor.

If you are taking dexketoprofen tablets, take them on an empty stomach or at least 30 minutes before eating, as they will increase the effectiveness of the drug. If you have a history of stomach ulcers, take this drug after eating.

If you forget to take dexketoprofen, take this medicine immediately if it is not close to the time for your next dose. Ignore the missed dose and do not double the dose of dexketoprofen, except as directed by your doctor.

Store dexketoprofen at room temperature, keep away from direct sunlight, and keep out of reach of children.

Dexketoprofen Interactions with Other Drugs

The following are some of the effects of interactions that may occur when dexketoprofen is used with other medicines:

  • Increased toxic effects of lithium , methotrexate, hydantoin, or sulfonamides
  • Increased risk of kidney damage if used with ciclosporin , tacrolimus, or ACE inhibitors
  • Decreased effectiveness of diuretic drugs or antihypertensive drugs
  • Increased risk of gastrointestinal bleeding if used with NSAIDs, aspirin , thrombolytic drugs, corticosteroids , antiplatelet agents, or anticoagulants , such as warfarin
  • Increased concentration of dexketoprofen in the blood when used with probenecid
  • Increased risk of hypoglycemia when used with sulfonylureas

Side Effects and Dangers of Dexketoprofen

Some side effects that may occur after using dexketoprofen are:

  • Dizzy
  • Nauseous
  • Vomit
  • Diarrhea
  • Heartburn

Check with your doctor if the side effects above don't go away or get worse. See your doctor right away if you have an allergic reaction to medication or have serious side effects, such as bloody or black stools, trouble breathing, severe stomach pain, or vomiting blood .

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