Dydrogesterone is a medicine to treat conditions caused by a lack of the hormone progesterone, such as menstrual disorders, recurrent miscarriages, infertility or infertility, or endometriosis.

Dydrogesterone belongs to a class of progestogen drugs which are a synthetic form of the hormone progesterone . Dydrogesterone can help regulate the normal growth and shedding of the uterine lining.

Dydrogesterone trademarks: Duphaston, Femoston Conti, Femoston

What is Dydrogesterone




Prescription drug


Treat menstrual disorders, recurrent miscarriage, threatened miscarriage, infertility or infertility, and endometriosis .

Consumed by


Dydrogesterone for pregnant and lactating women 

Category N: Not yet categorized. Whether dydrogesterone can be absorbed into breast milk or not is unknown. Pregnant and breastfeeding women should consult with their doctor before taking this drug.

Drug form

Film-coated tablets

Precautions Before Taking Dydrogesterone

Dydrogesterone is a hormonal drug that should not be taken carelessly. Before taking this drug, you need to pay attention to the following things:

  • Do not take dydrogesterone if you are allergic to this drug.
  • Tell your doctor if you have or have ever had heart disease, liver disease, breast cancer , unexplained extra-menstrual bleeding, porphyria , or depression .
  • Do not drive, use machinery, or do activities that require alertness, while taking dydrogesterone, because this drug can make you dizzy or drowsy.
  • Tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Immediately see a doctor if you experience an allergic drug reaction or overdose after taking dydrogesterone.

Dosage and Rules for Use Dydrogesterone

Dydrogesterone should only be used as prescribed by a doctor. The following is a general dosage for dydrogesterone based on its intended use:

Purpose: Treating dysmenorrhea  (painful menstruation)

  • 10 or 20 mg per day, starting on day 5–25 of the menstrual cycle.

Purpose: Treat endometriosis

  • 10–30 mg per day, starting on day 5–25 of the menstrual cycle.

Purpose: Treat abnormal uterine bleeding

  • The initial dose to stop bleeding is 20–30 mg daily, given for up to 10 days.
  • The maintenance dose is 10–20 mg daily during the second half of the menstrual cycle.

Purpose: Treat secondary amenorrhea

  • 10 or 20 mg daily for 14 days in the 2nd half of the menstrual cycle.

Purpose: Overcome premenstrual syndrome

  • 10 mg twice daily, starting from the 2nd half of the menstrual cycle until the first day of the next cycle.

Purpose: Overcoming irregular menstrual cycles

  • 10 or 20 mg per day, starting from the 2nd half of the menstrual cycle until the first day of the next cycle.

Purpose: Overcome the threat of miscarriage

  • Initial dose of 40 mg, followed by 20–30 mg daily until symptoms subside.

Purpose: Overcoming recurrent miscarriage

  • 10 mg twice daily, until the 12th week of pregnancy.

Purpose: Overcome infertility or infertility due to luteal insufficiency

  • 10–20 mg per day, starting from the second half of the menstrual cycle until the first day of the next cycle.

How to Take Dydrogesterone Correctly

Follow the doctor 's recommendations and read the information printed on the dydrogesterone packaging before starting to consume it. Dydrogesterone can be consumed before or after meals.

If you forget to take dydrogesterone, consume it as soon as you remember if the break with the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Try to take dydrogesterone at the same time every day so that the treatment is more effective.

Store dydrogesterone at room temperature. Do not store this medicine in a damp place or be exposed to direct sunlight. Keep dydrogesterone out of reach of children.

Dydrogesterone Interactions with Other Drugs

Dydrogesterone can cause drug interactions in the form of increased drug metabolism when used with  carbamazepine , efavirenz, phenobarbital , and rifampicin .

Dydrogesterone Side Effects and Dangers

Some of the side effects that can occur after consuming dydrogesterone are:

  • Headache
  • drowsiness
  • Dizzy
  • Nauseous
  • Vomit
  • Stomach ache
  • Vaginal bleeding
  • Breast pain
  • Mood swings

See a doctor if you experience any of the side effects mentioned above. Immediately consult a doctor if you experience a drug allergic reaction , such as swelling of the lips and eyelids, an itchy rash, or difficulty breathing, after taking dydrogesterone.



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