Gliquidone is a drug to lower blood sugar levels in  type 2 diabetics . The use of this medicine must be accompanied by the application of a healthy lifestyle in order for the treatment to be effective.

Gliquidone is a second generation sulfonylurea antidiabetic drug that works by stimulating insulin production and increasing carbohydrate metabolism. That way, blood sugar levels can be better controlled.

This drug can only work if the beta cells of the pancreas still produce insulin, so it cannot be used in the treatment of type 1 diabetes .

Gliquidone trademarks: Glurenorm, Gliquidone, Lodem

What is Gliquidone

Group Prescription drugs
Category Sulfonylurea antidiabetes
Benefits Treating type 2 diabetes
Consumed by Adults
Gliquidone for pregnant and lactating women Category N:  Not yet categorized.

It is not known whether Gliquidone is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without first consulting your doctor.

Drug form Tablets

Warnings Before Consuming Gliquidone

Gliquidone can only be used with a doctor's prescription. There are several things you should pay attention to before consuming gliquidone, among them:

  • Do not consume gliquidone if you are allergic to this medicine. Tell your doctor about your history of allergies, including if you have ever been allergic to  sulfa drugs .
  • Tell your doctor if you have had or are currently suffering from type 1 diabetes,   liver disease, heart disease, G6PD deficiency , kidney disease, porphyria , or adrenal gland disease .
  • Do not consume alcoholic beverages during treatment with gliquidone because it can increase the risk of hypoglycemia.
  • Tell the doctor that you are taking gliquidone before having surgery, including dental surgery.
  • Do not drive or do activities that require alertness after consuming gliquidone, because this drug can cause dizziness.
  • Tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
  • Tell your doctor if you are using certain medications, supplements, or herbal products.
  • See a doctor immediately if you experience an overdose or allergic reaction to a drug after consuming gliquidone.

Dosage and Administration of Gliquidone

The doctor will prescribe gliquidone according to the patient's condition. The general dose of gliquidone for adults with type 2 diabetes is 15 mg once a day.

The dose can be increased to reach a treatment dose of 45–60 mg per day which can be divided into 2–3 times of consumption. The maximum dose is 60 mg per drink or 180 mg per day.

How to Consume Gliquidone Correctly

Always follow the doctor 's advice and read the information on the medicine package before consuming gliquidone. Do not increase or decrease the dose of medicine without first consulting a doctor.

Gliquidone tablets are consumed with meals. Swallow gluquidone tablets whole with a glass of water. Consume gliquidone at the same time every day.

If you forget to take gliquidone, take it immediately when the break and the next consumption schedule is not too close. If it's close, ignore it and don't double the dose. Tell your doctor if you often forget to take gliquidone.

Gliquidone cannot cure type 2 diabetes. In order for the treatment to be more effective, patients must change their lifestyle to be healthier, such as adjusting their diet, exercising regularly, and quitting smoking.

Check with the doctor and check blood sugar regularly so that the response to therapy can be monitored.

Store gliquidone in a dry place, at room temperature, and away from sunlight. Keep out of the reach of children.

Interactions of Gliquidone with Other Drugs

The use of gliquidone together with other drugs can cause several interaction effects, among others:

  • Increased blood sugar lowering effect if used with ACE inhibitors, allopurinol , azole antifungals, cimetidine , clofibrate, anticoagulants , halofenate, octreotide , ranitidine, sulfinpyrazone, tricyclic antidepressants, MAOI , chloramphenicol, or tetracycline
  • Increased risk of hypoglycemia and masking symptoms of hypoglycemia if used with beta-blockers
  • Reduced blood sugar lowering effect if used with adrenaline, aminoglutethimide, diazoxide, rifamycin, chlorpromazine, corticosteroids, birth control pills , hormonal drugs, or thiazide diuretics

Side Effects and Dangers of Gliquidone

One of the side effects that can occur due to the use of gliquidone is hypoglycemia . Some symptoms of hypoglycemia are difficulty concentrating, trembling, paleness, cold sweats, or palpitations.

Immediately consume sweet food or drink if you feel the complaint. If the complaint gets worse, go to the doctor immediately.

In addition, some other side effects that can occur after consuming gliquidone:

  • Nausea
  • Vomiting
  • Stomachache
  • Diarrhea
  • Turn
  • Weight gain

Check with your doctor if the side effects do not subside or get worse. See a doctor immediately if you experience a drug allergic reaction that can be characterized by swelling of the lips or eyelids, a rash on the skin, or difficulty breathing.

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