Mebhydroline or mebhydrolin is a drug to relieve allergy symptoms, such as red eyes and runny nose, itchy skin rashes, nasal congestion due to allergic rhinitis , or shortness of breath. Mebhydrolin is available in the form of tablets, caplets, capsules and suspension.
Mebhydrolin is included in the 1st generation antihistamine drug group that works by reducing and preventing the effects of histamine, which are natural substances that cause allergic reactions, when the body is exposed to allergens (allergens). That way, allergy symptoms will subside.

Mebhydrolin trademarks: Biolergy, Gabiten, Histapan, Interhistin, Katergi, Mebhydroline Napadisilate, Omecidal, Tralgi, Zoline
What is Mebhydrolin
class | Prescription drug |
Category | Antihistamine |
Benefit | Relieves allergy symptoms |
Consumed by | Adults and children |
Mebhydrolin for pregnant and lactating women |
Category N: Not yet categorized.
It is not yet known whether Mebhydrolin is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
Drug form | Tablets, caplets, capsules and syrup (suspension) |
Precautions Before Taking Mebhydrolin
Mebhydrolin should only be used as prescribed by a doctor. Before using mebhydrolin, you need to pay attention to the following points:
- Do not use this drug if you are allergic to mebhydrolin. Always tell your doctor about any allergies you have.
- Tell your doctor if you have asthma . Mebhydrolin should not be used to treat acute asthma attacks.
- Do not give this medicine to newborns or premature babies.
- Tell your doctor if you have angle-closure glaucoma , enlarged prostate , difficulty urinating, epilepsy , or intestinal obstruction.
- Tell your doctor if you are taking any other medicines, including supplements and herbal products.
- Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
- Do not drive a vehicle or do activities that require alertness after taking mebhydrolin, because this drug can cause drowsiness.
- Immediately see a doctor if an allergic drug reaction or overdose occurs after taking this drug.
Dosage and Rules for Use Mebhydrolin
The doctor will adjust the dosage and rules for using mebhydrolin according to the condition and age of the patient. In general, the following is the dosage for treating allergies in adults and children:
- Adult: 100–300 mg per day
- Children >10 years: 100–300 mg daily
- Children 5-10 years: 100-200 mg per day
- Children 2-5 years: 50-150 mg per day
- Children <2 years: 50–100 mg daily
How to Take Mebhydrolin Correctly
Follow the doctor 's recommendations in consuming mebhydrolin and read the instructions for use found on the drug packaging. Mebhydrolin should be taken at mealtime or immediately after a meal.
Try to consume mebhydrolin in tablet, caplet, and capsule form as a whole. Do not split, chew or crush the medication as this can affect its effectiveness.
If you are going to take mebhydrolin suspension, shake the medicine first. Use the measuring spoon that is available in the drug packaging. Do not use a regular spoon to take the medicine, because the dosage may differ from the one prescribed.
If you forget to take the drug, consume it immediately if the time lag with the next dose is not too close. If it is close, ignore the dose and do not double the next dose.
Store mebhydrolin in a cool, dry place. Avoid drugs from hot temperatures and exposure to direct sunlight. Keep medicine out of reach of children.
Mebhydrolin Interactions with Other Drugs
Mebhydrolin can cause drug interaction effects if used together with other drugs, including:
- Increases the drowsiness effect if taken with drugs that have the effect of decreasing the activity of the central nervous system ( central nerve system depressants) or alcohol
- Increased effects of antimuscarinics, such as dry mouth , palpitations or blurred vision, when taken with MAOIs or atropine
- Mask the side effects of medications that can cause ear damage, such as aminoglycoside antibiotics
Mebhydrolin Side Effects and Dangers
Side effects that may occur after consuming mebhydrolin are:
- Drowsiness
- Headache
- Dry mouth
- Thicker phlegm
- Blurred vision
- Difficulty urinating (urine retention)
- Constipation ( constipation )
- Acid reflux ( GERD )
- Nauseous
- Vomit
- Diarrhea
Check with your doctor if the side effects above do not subside immediately or get worse. Immediately consult a doctor if you experience an allergic drug reaction or rare serious side effects, such as seizures , excessive sweating, muscle pain, tingling, tremors , sleep disturbances, confusion, or hair loss .