Nebivolol is a medicine to treat high blood pressure (hypertension) . Controlled blood pressure can reduce the risk of stroke, heart attack, or kidney problems. This drug can be used as a single treatment or in combination with other drugs. 

Nebivolol belongs to the class of beta blockers ( beta blockers ). This drug works by blocking beta receptors in the blood vessels and heart muscle thereby reducing tension in the heart and blood vessels, slowing the heart rate, and lowering blood pressure.

Apart from treating hypertension, nebivolol can also be used to treat heart failure. This medicine is only used with a doctor's prescription.

Trademarks of Nebivolol:  Linoven, Nebilet, Nebivolol, Nebivolol Hydrochloride, Nevodio

What is Nebivolol

class Prescription drug
Category Beta blockers ( beta blockers )
Benefit Treat hypertension and heart failure
Consumed by Adults and seniors over the age of 65 years


Nebivolol for pregnant and lactating women

Category C:  Animal studies have shown an adverse effect on the fetus, but there have been no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether Nebivolol is absorbed through breast milk or not. If you are breastfeeding, do not use this medication without telling your doctor.

Drug form Tablet

Precautions Before Taking Nebivolol

Nebivolol should only be used as prescribed by a doctor. The following are things you need to pay attention to before using nebivolol:

  • Tell your doctor about any history of allergies you have. Nebivolol should not be used by patients who are allergic to this drug.
  • Tell your doctor if you have severe liver disease, severe heart failure, or severe heart rhythm disturbances, including severe bradycardia or AV block. Nebivolol should not be used by patients with these conditions.
  • Tell your doctor if you have or have recently had  a heart attack .
  • Tell your doctor if you have or currently have asthma , kidney disease, liver disease , heart failure, depression, hyperthyroidism , diabetes, myasthenia gravis , pheochromocytoma, or Raynaud's syndrome .
  • Do not drive a vehicle or do activities that require alertness after taking nebivolol, because this drug can cause dizziness.
  • Tell your doctor if you are taking nebivolol before having any surgical procedure, including dental surgery.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Immediately see a doctor if you experience a drug allergic reaction, serious side effects or overdose after taking nebivolol.

Dosage and Rules for Use Nebivolol

The dose of nebivolol is determined based on the age, condition of the patient and the body's response to the drug. The following is the dose of nebivolol for adults based on the condition:

Condition: Hypertension

  • Adult: Initial dose of 5 mg once daily. Dosage may be increased after 2 weeks of treatment, according to patient response. Maximum dose of 40 mg, once a day.
  • Elderly over 65 years: Initial dose of 2.5 mg, once a day. Dosage can be increased to 5 mg once a day.

Condition: Heart failure

  • Adult: Initially 1.25 mg once daily. Maximum dose of 10 mg, once a day.

How to Take Nebivolol Properly

Use nebivolol as directed by your doctor and don't forget to read the information on the drug packaging. Do not increase or decrease your dose, and do not stop nebivolol without consulting your doctor first.

Take nebivolol at the same time every day for optimal treatment. Nebivolol can be taken before or after meals. Swallow nebivolol tablets with plain water.

If you forget to take nebivolol, take this drug immediately if the break with the next consumption schedule is not too close. If it's close, ignore it and don't double the dose.

Nebivolol can only control blood pressure, not to cure hypertension. Therefore, to maximize the effect of treatment, you are advised to adopt a healthy lifestyle, limit consumption of foods that contain lots of salt (sodium), and exercise regularly.

Store nebivolol in a closed container at room temperature, in a dry place, and avoid exposure to direct sunlight. Keep this drug out of reach of children.

Nebivolol Interactions with Other Drugs

The use of nebivolol together with other drugs can cause several interaction effects, including:

  • Increased effectiveness of aminophylline , diphylline , and theophylline , which can increase the risk of side effects, such as tremors or insomnia
  • Increased risk of heart rhythm disturbances when used with atazanavir, seritinib, dolasetron, or saquinavir
  • Increased risk of developing hypotension and bradycardia when used with verapamil , reserpine or clonidine
  • Increased levels and effects of disoptramide
  • Increased risk of developing severe bradycardia which can be fatal when used with fingolimod
  • Increased risk of side effects when used with diltiazem , digoxin or amiodarone
  • Decreased effectiveness of nebivolol when used with non-steroidal anti-inflammatory drugs , such as ibuprofen

Nebivolol Side Effects and Dangers

The following are some of the side effects that can occur after consuming nebivolol:

  • Dizziness or headache
  • Unusual fatigue
  • Insomnia
  • Heart rate feels slow
  • pins and needles
  • Nauseous

Check with your doctor if these side effects don't go away or get worse. Immediately consult a doctor if you experience an allergic drug reaction or serious side effects below:

  • Swelling in the limbs
  • Slow or irregular heartbeat
  • Hands and feet feel cold, blue, or numb
  • Chest pain
  • Hard to breathe
  • Dizzy like going to faint
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