Oxomemazine is a drug to relieve allergy symptoms, such as a runny or stuffy nose, coughing, sneezing, watery and itchy eyes, as well as itching or hives on the skin. This drug is available in the form of capsules and syrup.

Oxomemazine works by inhibiting the action of histamine, which is a compound that causes allergic symptoms when a person is exposed to a substance or ingredient that triggers allergies (allergens). In addition, oxomemazine also has an anticholinergic effect so that it can reduce mucus production in the nose and throat.

Because it can reduce phlegm, oxomemazine is often combined with guafenesin to treat coughs with phlegm. In addition, oxomemazine also causes drowsiness that can induce sleep. This can support cough healing.

Oxomemazine trademarks:  Comtusi, Comtusi Forte, Goxo, Oxopect, Oxoril, Oxfezin, Oroxin, Sanazol, Toplexil, Zemindo, Zemindo Forte

What is Oxomemazine

class Prescription drug
Category Antihistamine
Benefit Relieves allergy symptoms and pruritus. Treats cough with phlegm accompanied by allergies
Consumed by Adults and children
Oxomemazine for pregnant and lactating women Category C: There is not enough evidence from studies in experimental animals or humans to explain the safety of the drug for pregnant women and the fetus. Therefore, this drug should not be consumed by pregnant women, unless the doctor recommends it.

It is not known whether oxomemazine is absorbed into breast milk or not. If you are breastfeeding, do not take this drug without consulting your doctor first.

Drug form Capsules and syrup

Precautions Before Taking Oxomemazine

Oxomemazine should not be used carelessly. Before taking this drug, you need to pay attention to the following things:

  • Do not take oxomemazine if you have an allergy to this drug. Tell your doctor about any allergies you have.
  • Do not give oxomemazine to children younger than 2 years.
  • Tell your doctor if you have had or currently have benign prostate enlargement , glaucoma, paralytic ileus , myasthenia gravis, pyloric stenosis , asthma, chronic obstructive pulmonary disease , kidney disease, or liver disease.
  • Do not immediately drive a vehicle or do other activities that require alertness after taking oxomemazine, because this drug can cause dizziness or drowsiness.
  • Do not consume alcoholic beverages while on treatment with oxomemazine. Tell your doctor if you have trouble stopping or reducing your consumption of these drinks.
  • Tell your doctor that you are taking or have recently finished taking oxomemazine if you are planning to have an allergy test.
  • Be careful about using oxomemazine in the elderly, because the risk of side effects is greater.
  • Inform your doctor if you are taking other medications, including supplements and herbal products, to anticipate drug interactions.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Immediately see a doctor if you experience a drug allergic reaction or overdose after taking oxomemazine.

Dosage and Rules for Use Oxomemazine

The dose of oxomemazine can be different for each patient, depending on the severity of allergy symptoms. The usual dose of oxomemazine for adults is 5–13 mg daily, taken in 2–3 divided doses. While the dose for children will be determined directly by the doctor.

How to Take Oxomemazine Properly

Follow the doctor 's recommendations and read the information printed on the drug packaging before taking oxomemazine. Do not increase or decrease your dose without consulting your doctor.

Take oxomemazine regularly at the same time every day. Swallow the capsule with the help of plain water. If you are taking oxomemazine in syrup form, shake the package before taking the drug. Use the measuring spoon that is available in the package so that the dose consumed is correct.

If you forget to take oxomemazine, take this medicine immediately if it is not close to the next consumption schedule. If it is close, ignore the missed dose and do not double the next dose.

Store oxomemazine at room temperature. Do not store this medicine in a damp place or be exposed to direct sunlight. Keep oxomemazine out of reach of children.

Oxomemazine Interactions with Other Drugs

The use of oxomemazine together with barbiturate drugs , opioid painkillers, or sedatives can increase the risk of side effects in the form of excessive drowsiness, slowed breathing, decreased consciousness, and coma.

Oxomemazine Side Effects and Dangers

Some of the side effects that can occur after taking oxomemazine are:

  • Drowsiness
  • skin rash
  • Headache or dizziness ( vertigo )
  • Constipation
  • Dry mouth

Check with your doctor if the side effects above don't go away or get worse. Immediately see a doctor if an allergic drug reaction or serious side effects occur, such as:

  • Difficulty urinating
  • The skin is more sensitive to sunlight
  • Enlarged breasts in males ( gynecomastia )
  • Uncontrolled movements of the face
  • Weak muscles
Back to blog