Phenylpropanolamine or phenylpropanolamine hcl is a drug to relieve nasal congestion due to flu, cough, cold ( common cold ) , allergies, or inflammation of the sinuses (sinusitis). Phenylpropanolamine can be found in combination with other drugs.  

Phenylpropanolamine is a decongestant class of drugs that works by constricting the blood vessels in the nasal passages that were previously widened, so that the airways are more open and breathing becomes easier.

Keep in mind that this medicine can only relieve symptoms of nasal congestion and not cure the disease that is causing it.

Phenylpropanolamine trademarks:  Alpara , Dextrosin, Fluza, Fluza Day, Flutamol , Nalgestan , Nodrof Flu Expectorant, Paraflu, Procold Flu, Sanaflu, Tuzalos, Ultraflu

What is Phenylpropanolamine

class Over-the-counter and prescription drugs
Category decongestant
Benefit Relieves symptoms of a stuffy nose
Consumed by Adults and children
Phenylpropanolamine for pregnant and lactating women Category C:  Animal studies have shown an adverse effect on the fetus, but there have been no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Phenylpropanolamine can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Caplets, tablets and syrup

Precautions Before Taking Phenylpropanolamine

Before taking phenylpropanolamine, you need to pay attention to the following things:

  • Do not take phenylpropanolamine if you are allergic to this drug.
  • Do not drive or do activities that require alertness while being treated with phenylpropanolamine, because this drug can cause dizziness and  drowsiness .
  • Tell your doctor if you have hypertension , heart disease, arrhythmias , thyroid disease, intestinal obstruction , chronic constipation, diabetes , glaucoma, enlarged prostate , liver disease, or kidney disease .
  • Tell your doctor if you have ever had gallbladder disease, pancreatitis , a head injury, Addison's disease , asthma, sleep apnea , seizures, depression , or peptic ulcer .
  • Tell your doctor if you are taking or have recently taken an MAOI class of antidepressant drugs in the last 14 days. Phenylpropanolamine should not be used by these patients.
  • Phenylpropanolamine syrup products can contain artificial sweeteners, such as aspartame, which should not be consumed by people with phenylketonuria .
  • Do not give phenylpropanolamine to seniors over 60 years of age without consulting a doctor first.
  • Tell your doctor if you are taking certain medications, supplements or herbal products.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • See a doctor immediately if you have an allergic drug reaction , serious side effects, or an overdose after taking phenylpropanolamine.

Dosage and Rules for Using  Phenylpropanolamine

The dose of phenylpropanolamine varies for each patient. The following is the distribution of phenylpropanolamine doses to treat nasal congestion:

Caplet or tablet

  • Adult: 1–2 caplet/tablet, every 4 hours. Maximum dosage is 4–8 caplets/tablet per day.
  • Children 6–12 years: 1 caplet, every 4 hours. Maximum dosage is 4 caplets per day.

Sirop 2,5 mg/5 ml

  • Children aged 6 months–2 years: 2.5 ml, 3 times a day.
  • Children aged 3–5 years: 5 ml, 3–4 times a day.
  • Children 6–12 years: 5–10 ml, 3–4 times daily.

How to Take Phenylpropanolamine Properly

Follow the doctor 's advice and read the instructions listed on the drug packaging before taking phenylpropanolamine. Do not increase or decrease your dose without consulting your doctor first.

Phenylpropanolamine caplets, tablets, or syrup should be taken after meals to reduce the risk of stomach ulcers. Take phenylpropanolamine caplets or tablets with a glass of water to swallow the medication.

For phenylpropanolamine syrup, use the measuring spoon that is in the package so that the dosage is consumed correctly.

Make sure there is sufficient time between one dose and the next. Try to take phenylpropanolamine at the same time every day for maximum treatment.

If you forget to use phenylpropanolamine, it is advisable to use it immediately if the break with the next schedule is not too close. If it's close, ignore it and don't double the dose.

Do not take phenylpropanolamine for more than 7 days. Visit a doctor if the symptoms accompanied by high fever have not subsided after 1 week.

Store phenylpropanolamine at room temperature, and avoid exposure to direct sunlight. Keep medicine out of reach of children.

Phenylpropanolamine and Other Drug Interactions

The following are a number of drug interaction effects that can occur if you take phenylpropanolamine together with other drugs:

  • Increased risk of developing fatal hypertension when used with bromocriptine , indomethacin, or MAOI drugs, such as isocarboxid, linezolid, or phenelzine
  • Increased risk of psychosis when used with amantadine

Phenylpropanolamine Side Effects and Dangers

Some of the side effects that may appear after consuming phenylpherine are:

  • Dizzy
  • Lightheadedness
  • Drowsiness
  • Dry mouth
  • Nausea and Vomiting
  • Excessive sweating
  • Insomnia
  • Nervous
  • Tremor

Check with your doctor if the side effects above don't go away or get worse. See a doctor immediately if you have an allergic drug reaction or more serious side effects, such as:

  • Heart palpitations , fast or irregular heartbeat
  • Mental disturbances, moods, or hallucinations appear
  • Difficulty urinating
  • seizures
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