Selegiline is an adjunct medication used to control symptoms of Parkinson's disease. This drug will be prescribed along with other Parkinson's drugs , such as levodopa.

Selegiline works by increasing the amount of the hormone dopamine , which is a hormone that controls movement. Although it can be used as an adjunctive therapy to control complaints due to Parkinson's disease, this drug cannot cure this condition.

Selegiline trademark: Jumex

What is Selegiline

class MAOIs
Category Prescription drug
Benefit Controlling complaints in Parkinson's disease
Used by Adults and seniors
Selegiline for pregnant and lactating women Category C: Animal studies have shown an adverse effect on the fetus, but there have been no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not yet known whether selegiline will be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Form Tablet

Precautions Before Consuming Selegiline

Selegiline should not be used carelessly. Follow the doctor's recommendations while undergoing treatment with this drug. Before taking selegiline, you need to pay attention to the following things:

  • Do not take selegiline if you have a history of allergies to this drug.
  • Do not take selegiline if you are taking other antidepressant medicines, including fluoxetine .
  • Do not eat foods that are high in tyramine, such as beef and soybeans, while taking selegiline.
  • Do not do activities that require high alertness, such as driving a vehicle, after taking selegiline, because this drug can make you dizzy.
  • Tell your doctor if you are taking or have ever taken any medications, vitamin supplements, or herbal products.
  • Tell your doctor if you have liver disease , hypertension, kidney disease, phenylketonuria .
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • If an allergic drug reaction or overdose occurs after taking selegiline, see a doctor immediately.

Dosage and Rules for Use Selegiline

The dose of seregiline is determined based on the age and condition of the patient. The following are selegiline dosages based on their intended use:

  • Overcoming Parkinson's disease in adults
    Dosage: 5 mg, 2 times a day
    Maximum dose: 10 mg
  • Treating Parkinson's disease in the elderly
    Dosage: 5 mg, 2 times a day
    Maximum dose: 10 mg

Selegiline can also be used to treat depression. The type of selegiline preparation used to treat depression is a patch .

How to Take Selegiline Properly

When taking selegiline, follow the doctor's recommendations and read the instructions listed on the drug packaging. Selegiline can be consumed in the morning and afternoon.

Make sure you always take selegiline at the same time every day to get maximum results.

If you forget to take your medicine, take it as soon as you remember if it is not too close to the schedule for taking your next medicine. If it is close, ignore the missed dose and do not double the next dose.

Do not stop taking selegiline without consulting a doctor. While using this drug, do regular checkups with your doctor so that your health condition can be monitored.

Store selegiline in a tightly closed container. Make sure the container is out of reach of children. Store well at room temperature and make sure it is not stored in a place with a temperature that is too hot or in a damp place.

Selegiline Interactions with Other Drugs

Taking selegiline with other drugs can cause interaction effects in the form of:

  • Increased risk of developing hypertension when used with amphetamine , rasagiline, bupropion , and clonazepam
  • Increased risk of developing serotonin syndrome when used with antidepressant drugs , such as duloxetine, 5-hydroxytryptophan, escitalopram, and meperidine
  • Increased risk of respiratory distress and hypotension when used with opioid drugs
  • Increased side effects from levodopa

Selegiline can also increase your risk of developing a dangerous increase in blood pressure if you take it with foods or drinks that contain tyramine, such as sometimes soy, dried meat, or mushroom extracts.

Selegiline Side Effects and Dangers

There are some mild side effects that may occur after consuming selegiline, including:

  • Dizzy
  • Dry mouth
  • Stomach ache
  • Difficult to swallow
  • Drowsiness

Check with your doctor if the side effects above occur for a long time and are persistent. Apart from the side effects above, selegiline can cause side effects that are more serious and require examination by a doctor, such as:

  • Severe headache
  • Chest pain
  • Heart beat
  • Sweating
  • Nausea and vomiting
  • Stiff or sore neck
  • Uncontrollable body movements
  • Hallucinations
  • It's hard to breathe
Back to blog