Sotalol is a drug used to treat ventricular tachycardia or supraventricular tachycardia. This drug can also be used in the treatment of atrial fibrillation which causes severe symptoms, such as difficulty breathing. This medicine should only be used according to a doctor's prescription.

Sotalol is included in the beta blocker class of drugs that have antiarrhythmic effects. In low doses, this drug will work by blocking beta receptors in the heart and blood vessels. Thus, the heart rate will slow down.

In higher doses, sotalol has a class III antiarrhythmic effect and works by blocking potassium channels to normalize the rhythm of the heartbeat. 

Sotalol trademark: Sotalol Hydrochloride

What is Sotalol

class Prescription drug
Category Beta blocker
Benefit Treats some arrhythmic conditions, such as ventricular tachycardia or supraventricular tachycardia
Consumed by Adults and children over 12 years of age
Sotalol for pregnant and lactating women Category B: Animal studies have not demonstrated a risk to the fetus, but there are no controlled studies in pregnant women. Sotalol can be absorbed into breast milk, should not be used during breastfeeding.
Drug form Tablet

Precautions Before Consuming Sotalol

Sotalol should only be used as prescribed by a doctor. Here are some things you need to pay attention to before consuming sotalol:

  • Do not take sotalol if you are allergic to this drug. Tell your doctor about any history of allergies you have.
  • Tell your doctor if you have had or currently have long QT syndrome or other dangerous heart rhythm disturbances, such as severe bradycardia or AV block. Sotalol should not be given to patients suffering from this condition.
  • Tell your doctor if you have or have recently had a heart attack .
  • Tell your doctor if you have or currently have kidney disease , severe diarrhea, liver disease , low blood pressure, lung disease, heart disease, hyperthyroidism , diabetes, Raynaud's syndrome , low potassium blood level, or acidosis
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking any other medicines, including herbal medicines and supplements.
  • If you are planning to have surgery or certain medical procedures, tell your doctor that you are taking sotalol.
  • Immediately see a doctor if you have an allergic drug reaction , serious side effects, or an overdose after taking sotalol.

Dosage and Rules for Using Sotalol

The dose of sotalol given by the doctor depends on the health condition and age of the patient. Here is the explanation:

Condition: Management of ventricular tachycardia in an emergency setting

  • Adult: Initially 80 mg twice daily. Dosage may be increased every 3 days to 240–320 mg per day. Maintenance dose 160–320 mg per day in divided doses. Maximum dose 480–640 mg per day.

Condition: Supraventricular tachycardia or ventricular tachycardia

  • Adult: Initial dose of 80 mg per day. Dosage may be increased every 2–3 days. Maintenance dose 160–320 mg per day in divided doses.

The dosage for children will be determined by the doctor based on the child's weight and age.

How to Take Sotalol Properly

Take sotalol according to doctor 's advice and always read the instructions for use listed on the drug packaging. Do not reduce or increase your dose without consulting your doctor first.

Sotalol can be taken before or after meals. If you forget to take sotalol, take it as soon as you remember. If it is nearing time for your next dose, skip the missed dose. Do not double your sotalol dose to make up for a missed dose.

At the beginning of treatment, you will be asked to be in the hospital to monitor your condition, response to therapy, and side effects that can arise from taking sotalol.

While undergoing treatment with sotalol, you will be asked to periodically check your heart record or EKG .

Store sotalol at room temperature and place it in a closed container. Avoid this drug from exposure to direct sunlight and keep it out of reach of children.

Interactions of Sotalol with Other Drugs

The following are a number of interactions that can occur if sotalol is taken with other drugs:

  • Increased risk of bradycardia when taken with digoxin
  • Increased risk of arrhythmias if taken with diuretics , haloperidol,  macrolide antibiotics , or quinolones
  • Increased risk of developing hypertension if taken with clonidine
  • Decreased effectiveness of insulin or antidiabetic drugs
  • QT prolongation if taken with phenothiazine, terfenadine or astemizole
  • Increased risk of side effects if taken with diltiazem

Side Effects and Dangers of Sotalol

There are several side effects that can arise after consuming sotalol, including:

  • Dizziness or headache
  • Unusual fatigue
  • Diarrhea
  • Slow heart rate
  • Decreased sexual desire

Check with your doctor if the complaints mentioned above do not go away or get worse. Immediately see a doctor if you experience an allergic drug reaction or experience more serious side effects, such as:

  • Chest pain
  • Dizzy as if you want to faint
  • Heart rate slows, speeds up , or is irregular
  • Tingling or numbness in hands and feet
  • Swelling of the legs
  • Hard to breathe
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