Tiabendazole is a drug to treat infections caused by worms. This drug is available in the form of tablets and suspension . Tiabendazole is not used to prevent helminth infections.

This drug works by inhibiting the action of the fumarate reductase enzyme which is needed by worms to grow and develop, and inhibits the production and growth of worm eggs.

Tiabendazole can be used to treat diseases caused by worm infections, such as strongyloidiasis , cutaneous larva migrans , ascariasis , toxicculiasis , toxocariasis or trichuriasis . Tiabendazole is not used to treat mixed worm infections.

Trademarks of tiabendazole: -

What is Thiabendazole ?

class Prescription drug
Category Antihelmintic ( worm medicine )
Benefit Treat worm infections
Used by Mature
Tiabendazole for pregnant and lactating women Category C: Studies in experimental animals show an adverse effect on the fetus, but there have been no controlled studies in pregnant women. The drug should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether tiabendazole can be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug form Tablets and suspension

 Precautions Before Consuming Thiabendazole :

  • Do not take or use tiabendazole if you have a history of allergies to this drug.
  • Do not use tiabendazole as an anti-worm medication or to treat mixed worm infections.
  • Do not do activities that require high concentration, such as driving or operating machinery, after taking tiabendazole. This drug may cause dizziness and lightheadedness.
  • Tell your doctor if you have liver , kidney, or heart problems, anemia, or malnutrition.
  • Tell your doctor if you are pregnant, nursing, or planning a pregnancy before using tiabendazole.
  • Routine liver function tests may be performed while you are using tiabendazole. Make sure to follow the examination schedule given by the doctor.
  • If an allergic drug reaction or overdose occurs after using tiabendazole, see a doctor immediately.

Dosage and Rules for Using Thiabendazole

Tiabendazole is not used as a medicine to prevent worm infections. The dose of tiabendazole depends on the type of worm infection the patient is suffering from. The following details the dosage of tiabendazole based on the type of disease:

  • Strongyloidiasis
    Dosage: 25 mg/kg, 2 times a day, for 2 days; or 50 mg/kg in a single dose. If the infection has spread, this drug can be used for up to 5 days. The maximum dose is 3,000 mg per day.
  • Cutaneous larva migraine
    Dosage: 25 mg/kg, 2 times a day, for 2 days, the dose can be repeated after 2 days. The maximum dose is 3,000 mg per day.
  • Ascariasis and trichuriasis
    Dosage: 25 mg/kg, 2 times a day, for 2 days. The maximum dose is 3,000 mg per day.
  • Dracunculiasis
    Dosage: 25–50 mg/kg, 2 times a day, for a day. In severe infections, the dose may be increased to 50 mg/kg after 5-8 days. The maximum dose is 3,000 mg per day.
  • Toxocariasis
    Dosage: 25 mg/kg, 2 times a day, for 5–7 days. The maximum dose is 3,000 mg per day.

Interaction of Thiabendazole with Other Drugs

Tiabendazole can cause drug interaction effects when taken with other drugs. The resulting interaction effects include:

  • Inhibits the metabolism of theophylline and caffeine drugs
  • Increases the anti-clotting effect, when used with anticoagulant drugs , such as warfarin

How to Take Thiabendazole Correctly

Use tiabendazole according to the doctor's instructions or the information on the drug packaging.

This medicine should usually be taken after food. Medication in the form of tablets needs to be chewed before being swallowed, while drugs in the form of suspensions need to be shaken before drinking.

If you forget to take tiabendazole, take this drug as soon as you remember. Especially if the gap with the next dose schedule is not too close. If the time for the next dose is near, ignore the missed dose and do not double the dose.

This drug needs to be consumed until the time determined by the doctor, even though the symptoms of worm infection have subsided.

Store tiabendazole at room temperature. Avoid exposure to direct sunlight and keep this drug out of reach of children.

Tiabendazole Side Effects and Dangers

Some of the side effects that can be caused by tiabendazole are:

  • Dizzy
  • Headache
  • Ringing ears
  • Lost appetite
  • Nausea or vomiting
  • Diarrhea
  • Stomach ache

If the condition does not improve or even worsens, consult a doctor immediately. You are also advised to immediately see a doctor if you experience an allergic drug reaction or experience more serious side effects, namely:

  • Vision becomes blurry
  • Persistent diarrhea
  • Fever or chills
  • Yellowish skin and whites of the eyes ( jaundice )
  • seizures
  • Bloody urine
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