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Tirofiban is a drug to prevent blood clots in the arteries leading to the heart. This drug is sometimes also used to prevent the appearance of heart attacks in patients with angina pectoris. This medicine is available as an injection and is only given according to a doctor's prescription.

Tirofiban is an antiplatelet drug, which is a drug that works by preventing blood platelets from clotting, so that blood flow is not blocked. Tirofiban is used in patients with acute coronary syndrome. In addition, this drug can also be used in patients undergoing heart surgery or blood vessel surgery, such as angioplasty .

What Is Tirofiban?

Group Antiplatelet
Category Prescription drugs
Benefits Overcome acute coronary syndrome
Consumed by Adults
Tirofiban for pregnant and lactating women Category B: Studies on experimental animals do not show any risk to the fetus, but there are no controlled studies on pregnant women.

It is not yet known whether tirofiban can be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without first consulting a doctor.

Drug form Injection

Warnings Before Using Tirofiban:

  • Tell the doctor about the history of allergies you have, tirofiban should not be used in patients with a history of allergies to this drug.
  • Tirofiban should not be used in people who suffer from thrombocytopenia , gastrointestinal bleeding, are injured, or have undergone surgery in the previous 30 days. Tell your doctor if you have these conditions.
  • Do not consume alcoholic beverages while using tirofiban because it can increase the risk of intestinal or gastric bleeding.
  • Tell your doctor about your medical history, such as blood clotting disorders, liver disease, kidney disease, or hypertension .
  • Tell your doctor if you are planning a pregnancy, are pregnant, or are breastfeeding.
  • Inform the doctor of the medicines, supplements, including herbal medicines you are currently using, including if you are taking nonsteroidal anti-inflammatory drugs ( NSAIDs ).
  • Tirofiban can make you bleed easily. Be careful not to get injured while using this medicine.
  • Immediately see a doctor if you experience bruising, nosebleeds, bloody stools, bloody urine, bruises, after using tirofiban.
  • See a doctor immediately if you experience a drug allergic reaction or overdose after using tirofiban.

Tirofiban Dosage and Administration

Here is the dose of tirofiban in adults to overcome acute coronary syndrome:

  • Initial dose: 25 mcg/kgBW by injection into a vein (intravenous/IV) for 5 minutes.
  • Treatment dose: 0.15 mcg/kgBB/minute up to 18 hours

During the administration of tirofiban, the patient will be monitored by a doctor to ensure that the drug works well and does not cause side effects.

How to Use Tirofiban Correctly

Tirofiban is given by injection into a vein. This medicine can only be given by a doctor or by medical personnel under the supervision of a doctor.

While using tirofiban, patients will be asked to undergo routine blood tests and urine samples to avoid unwanted side effects.

Do not store tirofiban in the refrigerator. Store this medicine at room temperature and away from direct sunlight.

Interactions of Tirofiban with Other Drugs

Tirofiban can increase the risk of bleeding if used together with drugs that affect the blood clotting process, such as anticoagulants , glycoprotein IIb/IIIa inhibitors, and other antiplatelets, such as aspirin or ticagrelor.

Side Effects and Dangers of Tirofiban

Some of the side effects that may arise due to the use of tirofiban are:

  • Turn
  • Excessive sweating
  • Pain in the leg or pelvis
  • Heart rate slows down
  • Bruises
  • Nosebleed
  • Bleeding gums
  • Coughing blood
  • Bleeding CHAPTER

See a doctor immediately if the above side effects or drug allergic reactions appear, such as rash, facial swelling, and shortness of breath.

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