Voltadex is useful for relieving complaints of arthritis, muscles, or ligaments that can be caused by certain injuries or diseases, such as rheumatoid arthritis , osteoarthritis , or ankylosing spondylitis .

The main ingredient in Voltadex is diclofenac . This drug belongs to the group of non-steroidal anti-inflammatory drugs ( NSAIDs ). Diclofenac works by blocking the cyclooxygenase enzyme , which is the enzyme responsible for producing prostaglandins . When prostaglandins are reduced, pain and inflammation in the body will also subside.

Type and Content of Voltadex

There are 3 variants of Voltadex products available in Indonesia, namely:

  • Voltadex 25
    Each 1 Enteric Coated Voltadex 25 tablet contains 25 mg of diclofenac sodium . In 1 box contains 5 blisters, 1 blister contains 10 enteric coated tablets.
  • Voltadex 50
    Each 1 enteric-coated tablet Voltadex 50 contains 50 mg of diclofenac sodium . In 1 box containing 5 blisters or 10 blisters, 1 blister contains 10 enteric coated tablets.
  • Voltadex Gel
    Each 1 gram of Voltadex Gel 1% contains 11.6 mg of diclofenac diethylamine or the equivalent of 10 mg of diclofenac sodium . In 1 box contains 20 grams of Voltadex gel.

What is Voltadex

class Prescription medication for Voltadex tablets and limited over-the-counter medication for Voltadex Gel
Category Non-steroidal anti-inflammatory drugs (NSAIDs)
Benefit Relieves complaints of arthritis caused by certain injuries or diseases, such as rheumatoid arthritis , osteoarthritis , or ankylosing spondylitis
Used by Adults and children aged ≥6 years
Voltadex for pregnant and lactating women Category B for gel use: Animal studies have not demonstrated a risk to the fetus, but there have been no controlled studies in pregnant women.

Category C for tablet use <30 weeks' gestation:
Animal studies have shown adverse effects on the fetus, but there have been no controlled studies in pregnant women.
Drugs should only be used if the expected benefit outweighs the risk to the fetus.

Category D for tablet use at ≥30 weeks' gestation:
There is positive evidence of risk to the human fetus, but the benefits may outweigh the risks, for example in dealing with a life-threatening situation.

Voltadex in tablet form can be absorbed into breast milk, while Voltadex in gel form is not yet known whether it can be absorbed into breast milk or not.
Do not use this medication before consulting a doctor while breastfeeding.

Drug form Enteric coated tablets and gels

 Warning Before Using Voltadex

The following are some things you need to pay attention to before using Voltadex:

  • Do not use Voltadex if you are allergic to diclofenac. Tell your doctor if you are allergic to aspirin or other NSAIDs.
  • Tell your doctor if you have or have ever had hypertension, nasal polyps , heart disease, liver disease, kidney disease, stomach ulcer , anemia, gastrointestinal bleeding , asthma, edema , angioedema, or a blood clotting disorder.
  • Tell your doctor if you recently had a heart bypass procedure . Voltadex tablets should not be used in these conditions.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products, especially if you are taking SSRI antidepressants, diuretics , ACE inhibitors , anticoagulants , corticosteroids, ciclosporin, cholestyramine, tacrolimus , methotrexate, lithium , or voriconazole.
  • See a doctor immediately if you have an allergic drug reaction, serious side effects, or overdose after using Voltadex.

Dosage and Rules for Use Voltadex

The dosage of Voltadex prescribed by a doctor can vary for each patient. The following is the general dosage of Voltadex for adult and pediatric patients, which are divided based on the drug variant and the patient's condition:

Voltadex gel 1 %

Purpose: Relieves complaints of inflammation of the tendons, ligaments, muscles or joints , due to sprains , rheumatism or osteoarthritis

  • Adults: Apply 3-4 times a day on the affected part while rubbing it slowly.

Voltadex tablets 25 mg and Voltadex tablets 50 mg

Purpose: Relieve pain from non-rheumatic arthritis, rheumatoid arthritis , osteoarthritis , ankylosing spondylitis , or spondyloarthritis

  • Adult: Initially 25–50 mg 3 times daily. Maximum dose of 150 mg. Maintenance dose 75–100 mg once daily.
  • Children ≥6 years: 1–3 mg/kg in divided doses daily, as directed by the doctor.

How to Use Voltadex Properly

Follow the doctor 's advice and read the instructions printed on the package when using Voltadex.

Voltadex tablets should be taken after meals. Take Voltadex tablets with a glass of water or milk. Do not split, bite, or crush the tablet.

Apply Voltadex Gel to the sore area. Clean the area and dry it before applying the medication. Once the gel has been applied, gently scrub the area.

Do not apply Voltadex Gel to open wounds or areas of peeling skin. Do not apply sunscreen, moisturizer or cosmetics to the treated area. After using the medication, wait up to 10 minutes before covering the problem area with clothing.

Use Voltadex regularly at the same time every day so the drug can work more effectively.

If you forget to use the drug, do it immediately if the break with the next scheduled use is not too close. If it is close, ignore it and do not double the dose.

Store Voltadex in its packaging in a room that is not damp and is not exposed to direct sunlight. Do not put Voltadex in the freezer and keep the medicine out of the reach of children.

Voltadex Interactions with Other Drugs

The content of diclofenac in Voltadex can cause interaction effects when used with other drugs. Drug interactions that can occur include:

  • Increased risk of bleeding in the digestive tract when used with other NSAIDs, SSRI antidepressants , anticoagulant drugs, or corticosteroids
  • Increased risk of side effects on the heart and blood vessels when used with cardiac glycosides, such as digoxin
  • Increased risk of hyperkalemia and renal damage when used with ACE inhibitors , diuretics, ciclosporin or tacrolimus
  • Increased risk of drug toxicity when used with methotrexate , phenytoin or lithium.
  • Decreased effectiveness of diclofenac when used with cholestyramine
  • Increased blood levels of diclofenac when used with voriconazole

Voltadex Side Effects and Dangers

The use or consumption of drugs containing diclofenac can cause side effects. Side effects that can occur are:

  • Headache
  • Dizzy
  • Stomach ache
  • Feeling unwell
  • Diarrhea
  • A rash appears on the skin

Call your doctor if the side effects above don't go away or get worse. Immediately check with your doctor if you experience a drug allergic reaction which can be marked by the appearance of complaints, such as swollen lips or eyelids, skin rashes that are itchy and swollen, or difficulty breathing.

In addition, you should also see a doctor immediately if you have more serious side effects after using Voltadex, such as black, bloody bowel movements, vomiting that doesn't go away, jaundice , chest pain, or weakness on one side of the body. However, this side effect is rare.

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